Inulin prebiotic reinforces host cancer immunosurveillance
immunosurveillance
inulin
microbiota
prebiotic
ɣδ T cells
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2023
2023
Historique:
received:
21
11
2022
accepted:
06
02
2023
entrez:
6
3
2023
pubmed:
7
3
2023
medline:
8
3
2023
Statut:
epublish
Résumé
The gut microbiota is now recognized as a key parameter affecting the host's anti-cancer immunosurveillance and ability to respond to immunotherapy. Therefore, optimal modulation for preventive and therapeutic purposes is very appealing. Diet is one of the most potent modulators of microbiota, and thus nutritional intervention could be exploited to improve host anti-cancer immunity. Here, we show that an inulin-enriched diet, a prebiotic known to promote immunostimulatory bacteria, triggers an enhanced Th1-polarized CD4
Identifiants
pubmed: 36875124
doi: 10.3389/fimmu.2023.1104224
pmc: PMC9981629
doi:
Substances chimiques
Inulin
9005-80-5
Prebiotics
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1104224Informations de copyright
Copyright © 2023 Boucher, Plazy, Richard, Suau, Mangin, Cornet, Aldebert, Toussaint and Hannani.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Nature. 2023 Feb;614(7947):334-342
pubmed: 36697826
Nat Microbiol. 2021 Sep;6(9):1110-1117
pubmed: 34341528
PLoS One. 2013 Apr 22;8(4):e61217
pubmed: 23630581
J Immunol. 2019 Jul 15;203(2):311-320
pubmed: 31285310
Oncoimmunology. 2017 Sep 14;7(1):e1364828
pubmed: 29296515
Brief Bioinform. 2021 Nov 5;22(6):
pubmed: 34410336
Curr Nutr Rep. 2022 Sep;11(3):508-525
pubmed: 35704266
Cells. 2020 May 24;9(5):
pubmed: 32456316
Annu Rev Immunol. 2011;29:235-71
pubmed: 21219185
Sci Adv. 2020 Jan 29;6(5):eaax4690
pubmed: 32064335
Front Immunol. 2022 Jun 16;13:915837
pubmed: 35784326
Cell Rep. 2020 Feb 11;30(6):1753-1766.e6
pubmed: 32049008
Cell. 2016 Apr 7;165(2):276-87
pubmed: 27058662
EBioMedicine. 2017 Feb;15:8-9
pubmed: 27865766
Science. 2021 Dec 24;374(6575):1632-1640
pubmed: 34941392
Nat Med. 2015 Aug;21(8):938-945
pubmed: 26193342
Science. 2021 Dec 10;374(6573):eabf0095
pubmed: 34882451
Cancer Immunol Res. 2016 Mar;4(3):194-203
pubmed: 26787823
Eur J Immunol. 2009 Jun;39(6):1564-72
pubmed: 19405031
Cell Metab. 2012 Nov 7;16(5):559-64
pubmed: 23140640
Trends Immunol. 2007 Dec;28(12):514-8
pubmed: 17964854
Appl Environ Microbiol. 1997 Jul;63(7):2802-13
pubmed: 9212428
Nat Rev Immunol. 2017 Dec;17(12):733-745
pubmed: 28920588
Trends Immunol. 2012 May;33(5):199-206
pubmed: 22364810
Science. 2018 Jan 5;359(6371):104-108
pubmed: 29302014
Science. 2018 Jan 5;359(6371):97-103
pubmed: 29097493
Science. 2015 Nov 27;350(6264):1084-9
pubmed: 26541606
PLoS Med. 2022 Feb 8;19(2):e1003889
pubmed: 35134067
Nat Immunol. 2019 Feb;20(2):121-128
pubmed: 30664765
Science. 2013 Nov 22;342(6161):971-6
pubmed: 24264990
Oncoimmunology. 2019 Apr 17;8(8):1601483
pubmed: 31413911
Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):491-502
pubmed: 28611480
Nat Rev Immunol. 2013 Feb;13(2):88-100
pubmed: 23348415
J Immunol. 2008 May 1;180(9):6044-53
pubmed: 18424725
Expert Rev Vaccines. 2016 Jul;15(7):915-25
pubmed: 26890067
Science. 2018 Jan 5;359(6371):91-97
pubmed: 29097494
Nat Methods. 2010 May;7(5):335-6
pubmed: 20383131
Bioinformatics. 2018 Apr 15;34(8):1287-1294
pubmed: 29228191
Immunity. 2017 Apr 18;46(4):562-576
pubmed: 28423337
Eur J Clin Nutr. 2009 Nov;63(11):1277-89
pubmed: 19690573