Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke.
MucilAir™
cigarette
heated tobacco
in vitro
repeat exposure
tobacco harm reduction
Journal
Frontiers in toxicology
ISSN: 2673-3080
Titre abrégé: Front Toxicol
Pays: Switzerland
ID NLM: 101777990
Informations de publication
Date de publication:
2023
2023
Historique:
received:
21
10
2022
accepted:
09
01
2023
entrez:
6
3
2023
pubmed:
7
3
2023
medline:
7
3
2023
Statut:
epublish
Résumé
Tobacco harm reduction (THR) involves providing adult smokers with potentially reduced harm modes of nicotine delivery as alternatives to smoking combustible cigarettes. Heated tobacco products (HTPs) form a category with THR potential due to their ability to deliver nicotine and flavours through heating, not burning, tobacco. By eliminating burning, heated tobacco does not produce smoke but an aerosol which contains fewer and lower levels of harmful chemicals compared to cigarette smoke. In this study we assessed the
Identifiants
pubmed: 36875887
doi: 10.3389/ftox.2023.1076752
pii: 1076752
pmc: PMC9979258
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1076752Informations de copyright
Copyright © 2023 Chapman, Pour, Wieczorek, Trelles Sticken, Budde, Röwer, Otte, Mason, Czekala, Nahde, O’Connell, Simms and Stevenson.
Déclaration de conflit d'intérêts
Authors FC, EM, LC, GO’C, LS and MS were employed by the company Imperial Brands PLC. Authors SP, RW, ES, JB, KR, SO and TN were employed by the company Reemtsma Cigarettenfabriken GmbH, a subsidiary of Imperial Brands PLC.
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