Magnolia officinalis L. bark extract and respiratory diseases: From traditional Chinese medicine to western medicine via network target.
Magnolia officinalis L. extracts
airway diseases
antibacterial activity
nutraceutical
spontaneous and induced contractility
traditional Chinese medicine
Journal
Phytotherapy research : PTR
ISSN: 1099-1573
Titre abrégé: Phytother Res
Pays: England
ID NLM: 8904486
Informations de publication
Date de publication:
Jul 2023
Jul 2023
Historique:
revised:
25
01
2023
received:
04
07
2022
accepted:
09
02
2023
medline:
5
7
2023
pubmed:
8
3
2023
entrez:
7
3
2023
Statut:
ppublish
Résumé
The understanding of the use of Magnolia officinalis L. (Magnoliaceae) as a possible dietary supplement for supporting the treatment of airway pathologies might be of clinical interest. Two commercially available bark extracts (M. officinalis extract [MOE]) were characterized by quantitation in honokiol and magnolol content by means of high-performance liquid chromatography with UV detection. MOE effects, as well as those of the reference compounds per se, on some targets connected to airway pathologies (antibacterial- and lung and trachea relaxing- activities) were investigated. Results showed that MOE possessed interesting antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Streptococcus pneumoniae. This was accompanied by a spasmolytic and antispasmodic activity, possibly owing to its ability to concurrently modulate different targets such as H
Substances chimiques
magnolol
001E35HGVF
honokiol
11513CCO0N
Lignans
0
Biphenyl Compounds
0
Plant Extracts
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2915-2938Subventions
Organisme : University of Bologna
Organisme : University of Ferrara
Informations de copyright
© 2023 The Authors. Phytotherapy Research published by John Wiley & Sons Ltd.
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