A Functional Polymorphism in IL-1B Is Associated With Immune Reconstitution Inflammatory Syndrome of Chronic Disseminated Candidiasis.
Candida spp
IL-1B
cytokines
genetic polymorphism
immune inflammatory reconstitution syndrome
invasive fungal diseases
Journal
Open forum infectious diseases
ISSN: 2328-8957
Titre abrégé: Open Forum Infect Dis
Pays: United States
ID NLM: 101637045
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
received:
29
11
2022
accepted:
10
02
2023
entrez:
7
3
2023
pubmed:
8
3
2023
medline:
8
3
2023
Statut:
epublish
Résumé
We investigated single nucleotide polymorphisms (SNPs) possibly involved in immune reconstitution inflammatory syndrome of chronic disseminated candidiasis (IRIS-CDC) through a candidate gene approach and a prospective matched-control study. We found that an SNP located in interleukin-1B at rs1143627 was significantly associated with the risk of developing IRIS-CDC.
Identifiants
pubmed: 36879623
doi: 10.1093/ofid/ofad078
pii: ofad078
pmc: PMC9984983
doi:
Types de publication
Journal Article
Langues
eng
Pagination
ofad078Informations de copyright
© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
Déclaration de conflit d'intérêts
Potential conflicts of interest. Outside of the submitted work, B.R. has received travel grants from Pfizer and MSD and speaker's fees from MSD, Gilead, Astellas, and Iqone. S.A. has received travel grants from MSD and Gilead and speaker's fees from Gilead. P.Y.B. has received travel grants from Astellas, Pfizer, MSD, and Gilead and speaker's fees from MSD. O.L. has received speaker's fees from MSD, Gilead, Astellas, Pfizer, and F2G and has served as a consultant for Gilead. All other authors report no potential conflicts.
Références
Clin Infect Dis. 2005 Jun 15;40(12):1756-61
pubmed: 15909263
AIDS. 2013 Aug 24;27(13):2089-99
pubmed: 23525034
PLoS Pathog. 2014 Oct 16;10(10):e1004426
pubmed: 25329476
J Infect Dis. 2018 Apr 11;217(9):1408-1416
pubmed: 29390144
Front Immunol. 2021 Jan 27;11:621931
pubmed: 33584721
Haematologica. 2018 Nov;103(11):e527-e530
pubmed: 29880612
BMC Immunol. 2013 Aug 08;14:37
pubmed: 23927441
J Infect Dis. 2020 May 11;221(11):1907-1916
pubmed: 31879764
Microbes Infect. 2014 Aug;16(8):678-89
pubmed: 24980544
J Infect Dis. 2003 Apr 1;187(7):1153-6
pubmed: 12660931
Clin Infect Dis. 2008 Jun 15;46(12):1813-21
pubmed: 18462102
Med Mal Infect. 2018 May;48(3):202-206
pubmed: 29307444
Nat Med. 2016 Aug;22(8):952-60
pubmed: 27376574
Nature. 2000 Mar 23;404(6776):398-402
pubmed: 10746728
J Fungi (Basel). 2018 Dec 17;4(4):
pubmed: 30562960
Med Mycol. 2005 Jun;43(4):349-53
pubmed: 16110781