Post Radical Prostatectomy Erectile Dysfunction. A Single Centre Experience.
complications
erectile dysfunction
prostate cancer
radical prostatectomy
urologic oncology
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
accepted:
03
02
2023
entrez:
8
3
2023
pubmed:
9
3
2023
medline:
9
3
2023
Statut:
epublish
Résumé
This study aims to determine the effects of radical retropubic prostatectomy on post-operative erectile function. A total of 50 patients were included in this study, diagnosed with localized prostate cancer, and underwent nerve-sparing radical retropubic prostatectomy. All patients completed the International Index of Erectile Function (IIEF-5) questionnaire pre-operatively and on the third, sixth, and twelfth post-operative month and completed a self-reporting of their satisfaction with their sexual performance. Patients with a history of severe heart disease, were on erectile dysfunction medication, or had a score of 7 or less on the IIEF-5 questionnaire, were excluded from the study. Pre-operatively it was observed that the lower the IIEF-5 score, the higher the biopsy Gleason score. Post-operatively, 16 patients stated that erectile function had returned to the pre-operative IIEF-5 category. In contrast, only 13 of them stated they were happy with their sexual performance on the self-reporting scale. The rest reported dissatisfaction despite returning to their pre-operative erectile function status. IIEF-5 scores were also different when compared amongst the four age groups, with scores indicating that younger age is related to higher IIEF-5 scores. At the 3-month follow-up, no statistically significant difference was observed between age groups. Finally, patients younger than 64 reported significantly less deterioration in post-operative erectile function. Post-radical prostatectomy erectile dysfunction remains one of the most pressing issues in prostate cancer therapy. A higher Gleason score has a more significant impact on pre-operative ED, and at the same time, the best post-operative ED results are observed in younger patients. Finally, patients need extensive follow-up, therapy, and pre-and post-operative psychological support to have the best possible erectile function.
Identifiants
pubmed: 36883073
doi: 10.7759/cureus.34601
pmc: PMC9985922
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e34601Informations de copyright
Copyright © 2023, Pikramenos et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Urol Clin North Am. 2001 May;28(2):269-78
pubmed: 11402580
Crit Rev Oncol Hematol. 2002 Aug;43(2):141-51
pubmed: 12191736
Am Fam Physician. 2016 Nov 15;94(10):820-827
pubmed: 27929275
Zhonghua Nan Ke Xue. 2011 Dec;17(12):1146-51
pubmed: 22235687
Ther Umsch. 1998 Jun;55(6):352-6
pubmed: 9658975
BJU Int. 2012 Dec;110(11 Pt B):E541-6
pubmed: 22584031
J Med Life. 2017 Jan-Mar;10(1):13-18
pubmed: 28255370
Int Braz J Urol. 2015 Mar-Apr;41(2):265-73
pubmed: 26005967
Lancet. 2013 Jan 12;381(9861):153-65
pubmed: 23040455
Int J Impot Res. 2002 Aug;14(4):245-50
pubmed: 12152112
Rev Urol. 2005;7 Suppl 2:S11-7
pubmed: 16985892
Contemp Oncol (Pozn). 2015;19(6):471-3
pubmed: 26843845
Mod Pathol. 2018 Jan;31(S1):S47-63
pubmed: 29297487
CA Cancer J Clin. 2022 Jan;72(1):7-33
pubmed: 35020204
Int J Impot Res. 2011 Sep-Oct;23(5):181-92
pubmed: 21697860
Br J Gen Pract. 2021 Apr 29;71(706):e372-e380
pubmed: 33926885
J Sex Med. 2010 Apr;7(4 Pt 2):1598-607
pubmed: 20388160
Int Braz J Urol. 2013 Mar-Apr;39(2):173-81
pubmed: 23683664