Living donor liver transplant candidate and donor selection and engagement: Meeting report from the living donor liver transplant consensus conference.


Journal

Clinical transplantation
ISSN: 1399-0012
Titre abrégé: Clin Transplant
Pays: Denmark
ID NLM: 8710240

Informations de publication

Date de publication:
07 2023
Historique:
revised: 14 02 2023
received: 28 12 2022
accepted: 25 02 2023
medline: 14 7 2023
pubmed: 10 3 2023
entrez: 9 3 2023
Statut: ppublish

Résumé

Living donor liver transplantation (LDLT) is a promising option for mitigating the deceased donor organ shortage and reducing waitlist mortality. Despite excellent outcomes and data supporting expanding candidate indications for LDLT, broader uptake throughout the United States has yet to occur. In response to this, the American Society of Transplantation hosted a virtual consensus conference (October 18-19, 2021), bringing together relevant experts with the aim of identifying barriers to broader implementation and making recommendations regarding strategies to address these barriers. In this report, we summarize the findings relevant to the selection and engagement of both the LDLT candidate and living donor. Utilizing a modified Delphi approach, barrier and strategy statements were developed, refined, and voted on for overall barrier importance and potential impact and feasibility of the strategy to address said barrier. Barriers identified fell into three general categories: 1) awareness, acceptance, and engagement across patients (potential candidates and donors), providers, and institutions, 2) data gaps and lack of standardization in candidate and donor selection, and 3) data gaps regarding post-living liver donation outcomes and resource needs. Strategies to address barriers included efforts toward education and engagement across populations, rigorous and collaborative research, and institutional commitment and resources.

Identifiants

pubmed: 36892182
doi: 10.1111/ctr.14954
doi:

Types de publication

Consensus Development Conference Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e14954

Informations de copyright

© 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

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Auteurs

Michelle T Jesse (MT)

Transplant Institute, Henry Ford Health System, Detroit, Michigan, USA.

Whitney E Jackson (WE)

Division of Gastroenterology and Hepatology, University of Colorado, Aurora, Colorado, USA.

AnnMarie Liapakis (A)

Yale School of Medicine and Yale New Haven Transplant Center, New Haven, Connecticut, USA.

Swaytha Ganesh (S)

Thomas E Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Abhinav Humar (A)

Thomas E Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Nicolas Goldaracena (N)

Division of Transplant Surgery, University of Virginia Health System, Charlottesville, Virginia, USA.

Josh Levitsky (J)

Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

David Mulligan (D)

Division of Transplant Surgery, Yale University, New Haven, Connecticut, USA.

Elizabeth A Pomfret (EA)

Transplant Surgery, University of Colorado, Aurora, Colorado, USA.

Daniela P Ladner (DP)

Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

John P Roberts (JP)

UCSF Department of Surgery, San Francisco, California, USA.

Alisha Mavis (A)

Pediatric Gastroenterology, Hepatology, and Nutrition, Duke University Health, Durham, North Carolina, USA.

Carrie Thiessen (C)

University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

James Trotter (J)

Transplant Hepatology, Baylor University Medical Center, Dallas, Texas, USA.

Gerald Scott Winder (GS)

Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA.

Adam D Griesemer (AD)

Department of Surgery, NYU Langone Heath, New York, New York, USA.

Anjana Pillai (A)

Department of Internal Medicine, University of Chicago Medicine, Chicago, Illinois, USA.

Vineeta Kumar (V)

Department of Medicine, Division of Nephrology/Transplant, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Elizabeth C Verna (EC)

Center for Liver Disease and Transplantation, Columbia University, New York, New York, USA.

Dianne LaPointe Rudow (D)

Recanati/Miller Transplantation Institute, Mount Sinai Hospital, New York, New York, USA.

Hyosun H Han (HH)

Division of Gastrointestinal and Liver Diseases, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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