The connectome of an insect brain.

Animals Brain / ultrastructure Connectome Neurons / ultrastructure Synapses / ultrastructure Drosophila melanogaster / ultrastructure Nerve Net / ultrastructure

Journal

Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511

Informations de publication

Date de publication:
10 03 2023
Historique:
entrez: 9 3 2023
pubmed: 10 3 2023
medline: 14 3 2023
Statut: ppublish

Résumé

Brains contain networks of interconnected neurons and so knowing the network architecture is essential for understanding brain function. We therefore mapped the synaptic-resolution connectome of an entire insect brain (

Identifiants

DOI: 10.1126/science.add9330 PMID: 36893230 PMC: PMC7614541
pubmed: 36893230
doi: 10.1126/science.add9330
pmc: PMC7614541
mid: EMS175448
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadd9330

Subventions

Organisme : Wellcome Trust
ID : 205050
Pays : United Kingdom
Organisme : NIMH NIH HHS
ID : RF1 MH123233
Pays : United States
Organisme : Wellcome Trust
ID : 205038
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UP_1201/20
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UP_1201/21
Pays : United Kingdom

Commentaires et corrections

Type : CommentIn

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Auteurs

Michael Winding (M)

University of Cambridge, Department of Zoology, Cambridge, UK.
MRC Laboratory of Molecular Biology, Neurobiology Division, Cambridge, UK.
Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
ORCID: 0000-0003-1965-3266

Benjamin D Pedigo (BD)

Johns Hopkins University, Department of Biomedical Engineering, Baltimore, MD, USA.
ORCID: 0000-0002-9519-1190

Christopher L Barnes (CL)

MRC Laboratory of Molecular Biology, Neurobiology Division, Cambridge, UK.
University of Cambridge, Department of Physiology, Development, and Neuroscience, Cambridge, UK.
ORCID: 0000-0002-1296-7310

Heather G Patsolic (HG)

Johns Hopkins University, Department of Applied Mathematics and Statistics, Baltimore, MD, USA.
Accenture, Arlington, VA, USA.
ORCID: 0000-0001-8005-5455

Youngser Park (Y)

Johns Hopkins University, Center for Imaging Science, Baltimore, MD, USA.

Tom Kazimiers (T)

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
kazmos GmbH, Dresden, Germany.
ORCID: 0000-0002-1605-9475

Akira Fushiki (A)

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
ORCID: 0000-0002-7987-6405

Ingrid V Andrade (IV)

University of California Los Angeles, Department of Molecular, Cell and Developmental Biology, Los Angeles, CA, USA.

Avinash Khandelwal (A)

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
ORCID: 0000-0002-8756-1278

Javier Valdes-Aleman (J)

University of Cambridge, Department of Zoology, Cambridge, UK.
Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
ORCID: 0000-0002-1577-1057

Feng Li (F)

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.

Nadine Randel (N)

University of Cambridge, Department of Zoology, Cambridge, UK.
MRC Laboratory of Molecular Biology, Neurobiology Division, Cambridge, UK.
ORCID: 0000-0002-7817-4137

Elizabeth Barsotti (E)

MRC Laboratory of Molecular Biology, Neurobiology Division, Cambridge, UK.
University of Cambridge, Department of Physiology, Development, and Neuroscience, Cambridge, UK.
ORCID: 0000-0002-4106-5543

Ana Correia (A)

MRC Laboratory of Molecular Biology, Neurobiology Division, Cambridge, UK.
University of Cambridge, Department of Physiology, Development, and Neuroscience, Cambridge, UK.
ORCID: 0000-0001-7944-9326

Richard D Fetter (RD)

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
Stanford University, Stanford, CA, USA.
ORCID: 0000-0002-1558-100X

Volker Hartenstein (V)

University of California Los Angeles, Department of Molecular, Cell and Developmental Biology, Los Angeles, CA, USA.
ORCID: 0000-0001-9676-7393

Carey E Priebe (CE)

Johns Hopkins University, Department of Applied Mathematics and Statistics, Baltimore, MD, USA.
Johns Hopkins University, Center for Imaging Science, Baltimore, MD, USA.

Joshua T Vogelstein (JT)

Johns Hopkins University, Department of Biomedical Engineering, Baltimore, MD, USA.
Johns Hopkins University, Center for Imaging Science, Baltimore, MD, USA.
ORCID: 0000-0003-2487-6237

Albert Cardona (A)

MRC Laboratory of Molecular Biology, Neurobiology Division, Cambridge, UK.
Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
University of Cambridge, Department of Physiology, Development, and Neuroscience, Cambridge, UK.
ORCID: 0000-0003-4941-6536

Marta Zlatic (M)

University of Cambridge, Department of Zoology, Cambridge, UK.
MRC Laboratory of Molecular Biology, Neurobiology Division, Cambridge, UK.
Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
ORCID: 0000-0002-3149-2250

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › The connectome of an insect brain.
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › The connectome of an insect brain.
questionsmedicales.fr › Techniques d'investigation › Neuroimagerie › Neuroimagerie fonctionnelle › Cartographie cérébrale › Connectome › The connectome of an insect brain.
questionsmedicales.fr › Cellules › Neurones › The connectome of an insect brain.
questionsmedicales.fr › Cellules › Structures cellulaires › Membrane cellulaire › Structures de la membrane cellulaire › Jonctions intercellulaires › Synapses › The connectome of an insect brain.
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Insectes › Pterygota › Neoptera › Holometabola › Diptera › Drosophilidae › Drosophila › Drosophila melanogaster › The connectome of an insect brain.
questionsmedicales.fr › Système nerveux › Réseau nerveux › The connectome of an insect brain.