Developmental trajectory of transmission speed in the human brain.


Journal

Nature neuroscience
ISSN: 1546-1726
Titre abrégé: Nat Neurosci
Pays: United States
ID NLM: 9809671

Informations de publication

Date de publication:
04 2023
Historique:
received: 17 03 2022
accepted: 09 02 2023
medline: 7 4 2023
pubmed: 10 3 2023
entrez: 9 3 2023
Statut: ppublish

Résumé

The structure of the human connectome develops from childhood throughout adolescence to middle age, but how these structural changes affect the speed of neuronal signaling is not well described. In 74 subjects, we measured the latency of cortico-cortical evoked responses across association and U-fibers and calculated their corresponding transmission speeds. Decreases in conduction delays until at least 30 years show that the speed of neuronal communication develops well into adulthood.

Identifiants

pubmed: 36894655
doi: 10.1038/s41593-023-01272-0
pii: 10.1038/s41593-023-01272-0
pmc: PMC10076215
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

537-541

Subventions

Organisme : NIMH NIH HHS
ID : R01 MH122258
Pays : United States

Informations de copyright

© 2023. The Author(s).

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Auteurs

Dorien van Blooijs (D)

Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.
Stichting Epilepsie Instellingen Nederland (SEIN), Zwolle, the Netherlands.

Max A van den Boom (MA)

Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Department of Neurosurgery, Mayo Clinic, Rochester, MN, USA.

Jaap F van der Aar (JF)

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.

Geertjan M Huiskamp (GM)

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.

Giulio Castegnaro (G)

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.

Matteo Demuru (M)

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.

Willemiek J E M Zweiphenning (WJEM)

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.

Pieter van Eijsden (P)

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.

Kai J Miller (KJ)

Department of Neurosurgery, Mayo Clinic, Rochester, MN, USA.

Frans S S Leijten (FSS)

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.

Dora Hermes (D)

Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. hermes.dora@mayo.edu.

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