Indoor air surveillance and factors associated with respiratory pathogen detection in community settings in Belgium.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
11 03 2023
Historique:
received: 14 09 2022
accepted: 27 02 2023
entrez: 10 3 2023
pubmed: 11 3 2023
medline: 15 3 2023
Statut: epublish

Résumé

Currently, the real-life impact of indoor climate, human behaviour, ventilation and air filtration on respiratory pathogen detection and concentration are poorly understood. This hinders the interpretability of bioaerosol quantification in indoor air to surveil respiratory pathogens and transmission risk. We tested 341 indoor air samples from 21 community settings in Belgium for 29 respiratory pathogens using qPCR. On average, 3.9 pathogens were positive per sample and 85.3% of samples tested positive for at least one. Pathogen detection and concentration varied significantly by pathogen, month, and age group in generalised linear (mixed) models and generalised estimating equations. High CO

Identifiants

pubmed: 36898982
doi: 10.1038/s41467-023-36986-z
pii: 10.1038/s41467-023-36986-z
pmc: PMC10005919
doi:

Substances chimiques

Carbon Dioxide 142M471B3J

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1332

Informations de copyright

© 2023. The Author(s).

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Auteurs

Joren Raymenants (J)

Laboratory of Clinical Microbiology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium. joren.raymenants@kuleuven.be.
Department of General Internal Medicine, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium. joren.raymenants@kuleuven.be.

Caspar Geenen (C)

Laboratory of Clinical Microbiology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

Lore Budts (L)

Department of Laboratory Medicine, National Reference Center of Respiratory Pathogens, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Jonathan Thibaut (J)

Laboratory of Clinical Microbiology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

Marijn Thijssen (M)

Laboratory of Clinical and Epidemiological Virology (Rega Institute), KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

Hannelore De Mulder (H)

Laboratory of Clinical Microbiology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

Sarah Gorissen (S)

Laboratory of Clinical Microbiology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

Bastiaan Craessaerts (B)

Department of Laboratory Medicine, National Reference Center of Respiratory Pathogens, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Lies Laenen (L)

Laboratory of Clinical Microbiology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Department of Laboratory Medicine, National Reference Center of Respiratory Pathogens, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Kurt Beuselinck (K)

Department of Laboratory Medicine, National Reference Center of Respiratory Pathogens, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Sien Ombelet (S)

Department of Laboratory Medicine, National Reference Center of Respiratory Pathogens, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Els Keyaerts (E)

Department of Laboratory Medicine, National Reference Center of Respiratory Pathogens, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Emmanuel André (E)

Laboratory of Clinical Microbiology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Department of Laboratory Medicine, National Reference Center of Respiratory Pathogens, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

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