Antioxidant Activity of Different Tissues from Rabbits Fed Dietary Bovine Colostrum Supplementation.

antioxidant status bovine colostrum gene expression rabbit

Journal

Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614

Informations de publication

Date de publication:
26 Feb 2023
Historique:
received: 30 12 2022
revised: 23 02 2023
accepted: 24 02 2023
entrez: 11 3 2023
pubmed: 12 3 2023
medline: 12 3 2023
Statut: epublish

Résumé

Recent advances in animal nutrition have indicated that bovine colostrum (BC), due to its content of macronutrients, micronutrients and bioactive compounds, is an excellent health supplement. To the best of our knowledge, no studies on the effect of BC on antioxidant status have been performed in rabbits. This study aimed to investigate the effect of two BC concentrations on antioxidant status and gene expression of antioxidant enzymes in some tissues of rabbits. Thirty New Zealand White male rabbits were randomly divided into three experimental diets, containing 0% (CON), 2.5%, and 5% of BC (BC-2.5 and BC-5, respectively). The activity of antioxidant enzymes in plasma (catalase: CAT; glutathione peroxidase: GPx; superoxide dismutase: SOD), and the enzymes' gene expression in the liver and longissimus dorsi muscle, were determined. Results showed no significant differences, neither in plasma nor in tissues. A significant tissue-related effect has been observed regarding the mRNA levels of SOD and GPx, which were higher in the LD (

Identifiants

pubmed: 36899707
pii: ani13050850
doi: 10.3390/ani13050850
pmc: PMC10000081
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : University of Milano
ID : UNIMI Research Support Plan - Call Line 2 2020

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Auteurs

Valentina Serra (V)

Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

Marta Castrica (M)

Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

Stella Agradi (S)

Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

Giulio Curone (G)

Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

Daniele Vigo (D)

Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

Alessia Di Giancamillo (A)

Department of Biomedical Sciences for Health, University of Milan, Via Mangiagalli 31, 20133 Milan, Italy.

Silvia Clotilde Modina (SC)

Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

Federica Riva (F)

Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

Claudia Maria Balzaretti (CM)

Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

Roberta De Bellis (R)

Department of Biomolecular Sciences, University of Urbino "Carlo Bo", Via A. Saffi 2, 61029 Urbino, Italy.

Gabriele Brecchia (G)

Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

Grazia Pastorelli (G)

Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

Classifications MeSH