The Resection Rate of Synchronously Detected Liver and Lung Metastasis from Colorectal Cancer Is Low-A National Registry-Based Study.
colorectal cancer
incidence
liver metastases
lung metastases
synchronous metastases
treatment
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
23 Feb 2023
23 Feb 2023
Historique:
received:
27
01
2023
revised:
21
02
2023
accepted:
22
02
2023
entrez:
11
3
2023
pubmed:
12
3
2023
medline:
12
3
2023
Statut:
epublish
Résumé
Population-based data on the incidence and surgical treatment of patients with colorectal cancer (CRC) and synchronous liver and lung metastases are lacking as are real-life data on the frequency of metastasectomy for both sites and outcomes in this setting. This is a nationwide population-based study of all patients having liver and lung metastases diagnosed within 6 months of CRC between 2008 and 2016 in Sweden identified through the merging of data from the National Quality Registries on CRC, liver and thoracic surgery and the National Patient Registry. Among 60,734 patients diagnosed with CRC, 1923 (3.2%) had synchronous liver and lung metastases, of which 44 patients had complete metastasectomy. Surgery of liver and lung metastases yielded a 5-year OS of 74% (95% CI 57-85%) compared to 29% (95% CI 19-40%) if liver metastases were resected but not the lung metastases and 2.6% (95% CI 1.5-4%) if non-resected,
Identifiants
pubmed: 36900225
pii: cancers15051434
doi: 10.3390/cancers15051434
pmc: PMC10000535
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Stockholm County Council
ID : clinical postdoctoral appointment 2020-2023
Organisme : Karolinska Institute
ID : Ruth and Richard Julin Foundation
Références
Br J Surg. 2012 Sep;99(9):1263-9
pubmed: 22864887
Digestion. 2020;101(2):144-155
pubmed: 30783050
BMC Cancer. 2018 Jan 15;18(1):78
pubmed: 29334918
Clin Exp Metastasis. 2015 Jun;32(5):457-65
pubmed: 25899064
Cancers (Basel). 2020 Jul 03;12(7):
pubmed: 32635230
Acta Oncol. 2018 Dec;57(12):1611-1621
pubmed: 30477372
Br J Surg. 2015 Feb;102(3):261-8
pubmed: 25529247
Ann Oncol. 2016 Aug;27(8):1386-422
pubmed: 27380959
Br J Surg. 2013 Nov;100(12):1627-32
pubmed: 24264786
Acta Oncol. 2021 Jul;60(7):842-849
pubmed: 33689551
Colorectal Dis. 2021 Jun;23(6):1306-1316
pubmed: 33368958
Eur J Surg Oncol. 2020 Mar;46(3):476-485
pubmed: 31837931
Am J Surg. 2020 Jan;219(1):80-87
pubmed: 31217074
Ann Thorac Surg. 2019 Feb;107(2):631-649
pubmed: 30476477
Br J Surg. 2015 May;102(6):691-9
pubmed: 25789941
Ann Surg. 2015 Jul;262(1):112-20
pubmed: 25373464
Sci Rep. 2016 Jul 15;6:29765
pubmed: 27416752
Br J Surg. 2014 Apr;101(5):550-7
pubmed: 24756914
Ann Surg Treat Res. 2017 Feb;92(2):82-89
pubmed: 28203555
Control Clin Trials. 1996 Aug;17(4):343-6
pubmed: 8889347
Eur J Surg Oncol. 2021 Feb;47(2):311-316
pubmed: 32873452
Oncologist. 2017 Sep;22(9):1067-1074
pubmed: 28550028
Colorectal Dis. 2020 Oct;22(10):1314-1324
pubmed: 32388895
JAMA Surg. 2015 Mar 1;150(3):245-51
pubmed: 25588105
Eur J Surg Oncol. 2022 Aug;48(8):1799-1806
pubmed: 35305858
Br J Surg. 2021 Jul 23;108(7):817-825
pubmed: 33749772
BMC Cancer. 2020 Mar 23;20(1):246
pubmed: 32293337
Ann Surg Oncol. 2013 May;20(5):1567-74
pubmed: 23124860
Ann Surg Oncol. 2015 May;22(5):1585-92
pubmed: 25373535
Scand J Surg. 2018 Dec;107(4):294-301
pubmed: 29692213
Ann Oncol. 2023 Jan;34(1):10-32
pubmed: 36307056
BJS Open. 2020 Aug;4(4):685-692
pubmed: 32543788
J Hepatobiliary Pancreat Sci. 2022 Jan;29(1):6-15
pubmed: 34866349
Ann Surg Oncol. 2015 Jul;22(7):2179-94
pubmed: 25582739
Hepatobiliary Surg Nutr. 2020 Feb;9(1):49-58
pubmed: 32140478
BJS Open. 2020 Aug;4(4):645-658
pubmed: 32484318