Biomarkers and their potential for detecting livestock plant poisonings in Western North America.
Plants poisonous to livestock
ear wax
larkspurs
lupine (Lupinus spp.)
pyrrolizidine alkaloid (PA)
selenium toxicity in animals
swainsonine
water hemlock
Journal
Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658
Informations de publication
Date de publication:
2023
2023
Historique:
received:
21
11
2022
accepted:
03
02
2023
entrez:
13
3
2023
pubmed:
14
3
2023
medline:
14
3
2023
Statut:
epublish
Résumé
The United States National Cancer Institute defines a biomarker as: "A biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease." In Veterinary Medicine, biomarkers associated with plant poisonings of livestock have great utility. Since grazing livestock poisoned by toxic plants are often found dead, biomarkers of plant poisoning allow for a more rapid postmortem diagnosis and response to prevent further deaths. The presence and concentration of toxins in poisonous plants are biomarkers of risk for livestock poisoning that can be measured by the chemical analysis of plant material. More difficult is, the detection of plant toxins or biomarkers in biological samples from intoxicated or deceased animals. The purpose of this article is to review potential biomarkers of plant poisoning in grazing livestock in the Western North America including recently investigated non-invasive sampling techniques. Plants discussed include larkspur, lupine, water hemlock, swainsonine-containing plants, selenium-containing plants, and pyrrolizidine alkaloid containing plants. Other factors such as animal age and sex that affect plant biomarker concentrations
Identifiants
pubmed: 36908517
doi: 10.3389/fvets.2023.1104702
pmc: PMC9992831
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1104702Informations de copyright
Copyright © 2023 Green, Welch, Lee, Stonecipher, Gardner, Stegelmeier, Davis and Cook.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Pharmacol Exp Ther. 1999 Nov;291(2):538-46
pubmed: 10525069
Birth Defects Res C Embryo Today. 2013 Dec;99(4):223-34
pubmed: 24339034
J Anim Sci. 1988 Sep;66(9):2407-13
pubmed: 3049497
Front Microbiol. 2022 May 03;13:871148
pubmed: 35591984
J Toxicol Environ Health. 1976 Jul;1(6):887-98
pubmed: 966318
J Nat Prod. 1995 Jun;58(6):863-9
pubmed: 7673930
FEBS Lett. 1983 Oct 31;163(1):110-3
pubmed: 6414843
J Vet Diagn Invest. 2012 Mar;24(2):319-27
pubmed: 22379047
J Anim Sci. 2019 Mar 1;97(3):1424-1432
pubmed: 30772914
Res Vet Sci. 2017 Dec;115:195-200
pubmed: 28494312
J Anim Sci. 2015 Aug;93(8):4181-8
pubmed: 26440198
Am J Vet Res. 2009 Apr;70(4):539-46
pubmed: 19335112
J Anim Sci. 2013 Sep;91(9):4501-9
pubmed: 23825349
Biochem J. 1984 Aug 1;221(3):601-7
pubmed: 6433887
Toxicon. 2017 Jul;133:91-94
pubmed: 28479311
J Appl Toxicol. 2013 Sep;33(9):1011-6
pubmed: 23296980
J Vet Diagn Invest. 1996 Oct;8(4):474-80
pubmed: 8953535
Am J Vet Res. 2009 Jul;70(7):926-31
pubmed: 19566479
J Chem Ecol. 2002 Nov;28(11):2327-41
pubmed: 12523572
J Anim Sci. 2008 Oct;86(10):2761-70
pubmed: 18539831
J Chem Ecol. 2009 Jun;35(6):643-52
pubmed: 19459011
Toxicon. 2015 Jun 1;99:36-43
pubmed: 25772859
Toxicon. 2015 Nov;106:1-6
pubmed: 26341422
Toxicon. 2017 Dec 1;139:54-57
pubmed: 28964750
Toxicon. 2018 Sep 15;152:57-59
pubmed: 30055258
J Chem Ecol. 2007 Jan;33(1):75-84
pubmed: 17146716
Mycol Res. 2003 Aug;107(Pt 8):980-8
pubmed: 14531620
J Agric Food Chem. 2013 Apr 24;61(16):3797-803
pubmed: 23547913
Vet Clin North Am Food Anim Pract. 2020 Nov;36(3):715-723
pubmed: 33032701
J Agric Food Chem. 2009 Feb 25;57(4):1646-53
pubmed: 19182952
Experientia. 1979 Oct 15;35(10):1367-8
pubmed: 499426
Toxicon. 2015 Dec 15;108:11-4
pubmed: 26415905
J Anim Sci. 2012 Jul;90(7):2394-401
pubmed: 22247113
Am J Vet Res. 2010 Apr;71(4):487-92
pubmed: 20367059
J Vet Diagn Invest. 1994 Oct;6(4):473-9
pubmed: 7858027
Toxicon. 2019 Apr 1;161:33-39
pubmed: 30826472
Am J Vet Res. 2011 May;72(5):706-14
pubmed: 21529225
J Agric Food Chem. 2014 Jul 30;62(30):7326-34
pubmed: 24758700
J Nat Prod. 1984 Nov-Dec;47(6):1030-2
pubmed: 6533262
FEBS Lett. 1983 Oct 31;163(1):99-103
pubmed: 6628696
J Nutr. 1988 Jun;118(6):747-55
pubmed: 2897437
Toxicon. 2022 Jan 15;205:79-83
pubmed: 34871669
Chem Res Toxicol. 2013 Aug 19;26(8):1129-38
pubmed: 23848825
Toxicon. 2017 Sep 1;135:12-16
pubmed: 28576552
J Nat Prod. 2013 Oct 25;76(10):1984-8
pubmed: 24053110
Toxicon. 2019 Jul;165:31-39
pubmed: 31029637
J Agric Food Chem. 2018 Feb 28;66(8):1773-1783
pubmed: 29372639
Toxicon. 2017 Oct;137:54-57
pubmed: 28716647
Teratology. 1989 Nov;40(5):423-32
pubmed: 2623630
Toxicon. 2019 Apr 1;161:1-3
pubmed: 30825462
Toxins (Basel). 2016 Nov 29;8(12):
pubmed: 27916846
Anal Bioanal Chem. 2013 May;405(13):4409-17
pubmed: 23420136
J Vet Diagn Invest. 1995 Jul;7(3):364-73
pubmed: 7578453
Toxicon. 2020 Mar;176:55-58
pubmed: 32103796
Food Chem Toxicol. 2013 Aug;58:8-13
pubmed: 23603380
Vet Clin North Am Food Anim Pract. 1993 Mar;9(1):33-40
pubmed: 8457928
Toxicon. 2016 Aug;118:104-11
pubmed: 27085305
J Nat Toxins. 1999 Feb;8(1):53-62
pubmed: 10091128
Vet Clin North Am Food Anim Pract. 2020 Nov;36(3):661-671
pubmed: 33032697
J Anim Sci. 2019 Mar 1;97(3):1415-1423
pubmed: 30772897
Neurotoxicol Teratol. 2010 May-Jun;32(3):383-90
pubmed: 20116429
FEBS Lett. 1983 Oct 31;163(1):104-9
pubmed: 6628681
J Vet Diagn Invest. 1999 Sep;11(5):448-56
pubmed: 12968759
J Nat Toxins. 1998 Jun;7(2):131-40
pubmed: 9678187
Res Vet Sci. 2015 Jun;100:239-44
pubmed: 25912242
Am J Vet Res. 2012 Aug;73(8):1318-24
pubmed: 22849693
J Vet Diagn Invest. 2006 Jan;18(1):61-70
pubmed: 16566258
Vet Clin North Am Food Anim Pract. 2020 Nov;36(3):775-789
pubmed: 32943303
Res Vet Sci. 2013 Oct;95(2):612-5
pubmed: 23664180
J Nat Toxins. 1999 Feb;8(1):95-116
pubmed: 10091131
Toxicon. 2009 Apr;53(5):591-4
pubmed: 19673106
Vet Clin North Am Food Anim Pract. 2011 Jul;27(2):419-28, ix
pubmed: 21575778
J Agric Food Chem. 2007 Dec 26;55(26):10649-55
pubmed: 18038992
J Agric Food Chem. 2014 Jul 30;62(30):7393-7
pubmed: 24829058
J Appl Toxicol. 2011 Jan;31(1):20-6
pubmed: 20635330
J Agric Food Chem. 2019 Jan 9;67(1):43-49
pubmed: 30525551
J Agric Food Chem. 1999 Dec;47(12):5049-58
pubmed: 10606571
J Nat Toxins. 1999 Feb;8(1):35-45
pubmed: 10091126
J Anim Sci. 2013 Dec;91(12):5970-80
pubmed: 24085414
J Appl Toxicol. 2016 May;36(5):716-25
pubmed: 26177929
Birth Defects Res C Embryo Today. 2013 Dec;99(4):235-46
pubmed: 24339035
J Pharmacol Exp Ther. 2013 Jan;344(1):295-307
pubmed: 23086230
Phytochem Anal. 2012 May-Jun;23(3):278-84
pubmed: 21953740