Smaug regulates germ plasm synthesis and primordial germ cell number in Drosophila embryos by repressing the

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
27 Feb 2023
Historique:
pubmed: 14 3 2023
medline: 14 3 2023
entrez: 13 3 2023
Statut: epublish

Résumé

During Drosophila oogenesis, the Oskar (OSK) RNA-binding protein (RBP) determines the amount of germ plasm that assembles at the posterior pole of the oocyte. Here we identify the mechanisms that regulate the

Identifiants

DOI: 10.1101/2023.02.27.530189 PMID: 36909513 PMC: PMC10002672
pubmed: 36909513
doi: 10.1101/2023.02.27.530189
pmc: PMC10002672
pii:
doi:

Types de publication

Preprint

Langues

eng

Déclaration de conflit d'intérêts

Competing interests: All authors declare they have no competing interests.

Auteurs

Najeeb U Siddiqui (NU)

Department of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.
Program in Developmental & Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada M5G 0A4.

Angelo Karaiskakis (A)

Department of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.

Aaron L Goldman (AL)

Department of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.
Program in Developmental & Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada M5G 0A4.

Whitby V I Eagle (WVI)

Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.

Craig A Smibert (CA)

Department of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.
Department of Biochemistry, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.

Elizabeth R Gavis (ER)

Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.

Howard D Lipshitz (HD)

Department of Molecular Genetics, University of Toronto, 661 University Avenue, Toronto, Ontario, Canada M5G 1M1.

Classifications MeSH