Coenzyme Q

Blood brain barrier Coenzyme-Q10 Inflammation Oxidative stress Trypanosoma brucei rhodesiense

Journal

Journal of parasitic diseases : official organ of the Indian Society for Parasitology
ISSN: 0971-7196
Titre abrégé: J Parasit Dis
Pays: India
ID NLM: 9713059

Informations de publication

Date de publication:
Mar 2023
Historique:
received: 15 07 2022
accepted: 21 11 2022
pmc-release: 01 03 2024
entrez: 13 3 2023
pubmed: 14 3 2023
medline: 14 3 2023
Statut: ppublish

Résumé

During the late stage of Human African Trypanosomiasis (HAT), there is severe cytokine-driven inflammation, oxidative stress and organ damage. Controlling inflammation and oxidative damage presents unique therapeutic opportunities to improve treatment outcome. The current study sought to determine the putative impact of Coenzyme-Q10 (Co-Q

Identifiants

pubmed: 36910316
doi: 10.1007/s12639-022-01553-8
pii: 1553
pmc: PMC9998817
doi:

Types de publication

Journal Article

Langues

eng

Pagination

167-184

Informations de copyright

© Indian Society for Parasitology 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Déclaration de conflit d'intérêts

Conflict of interestThe authors have declared that no conflict of interests exist.

Références

J Clin Invest. 2006 Oct;116(10):2739-47
pubmed: 16998589
Neuropsychiatr Dis Treat. 2009;5:597-610
pubmed: 19966907
PLoS One. 2010 Oct 01;5(10):
pubmed: 20957049
Cell Immunol. 1999 Feb 25;192(1):24-32
pubmed: 10066343
Int J Parasitol Parasites Wildl. 2019 Mar 24;9:16-20
pubmed: 30976512
Trop Biomed. 2016 Jun 1;33(2):209-225
pubmed: 33579087
Arthritis Res Ther. 2010;12(2):206
pubmed: 20441605
Ann Med. 2000 May;32(4):274-8
pubmed: 10852144
PLoS One. 2017 Jan 26;12(1):e0170172
pubmed: 28125601
CNS Neurol Disord Drug Targets. 2013 Aug;12(5):641-64
pubmed: 23574157
Blood. 2017 Mar 23;129(12):1571-1572
pubmed: 28336729
Int J Vitam Nutr Res. 1975;45(4):388-95
pubmed: 1213865
Exp Parasitol. 1976 Dec;40(3):427-31
pubmed: 976425
J Clin Invest. 2004 Feb;113(4):496-504
pubmed: 14966556
Neurobiol Dis. 2005 Apr;18(3):618-27
pubmed: 15755687
Front Immunol. 2018 Feb 15;9:218
pubmed: 29497418
Lancet Infect Dis. 2002 Jul;2(7):437-40
pubmed: 12127356
Cell Host Microbe. 2016 Jun 8;19(6):837-48
pubmed: 27237364
An Acad Bras Cienc. 2006 Dec;78(4):645-65
pubmed: 17143404
Biofactors. 2008;32(1-4):129-33
pubmed: 19096108
Nature. 2003 Oct 2;425(6957):516-21
pubmed: 14520412
Haematologica. 2021 Mar 01;106(3):806-818
pubmed: 31919087
Lipids Health Dis. 2018 Oct 9;17(1):230
pubmed: 30296936
J Neuroimmunol. 2005 Oct;167(1-2):81-9
pubmed: 16054238
J Inflamm (Lond). 2019 Mar 18;16:5
pubmed: 30923464
Philos Trans R Soc Lond B Biol Sci. 2015 Aug 19;370(1675):
pubmed: 26150654
Nutrients. 2019 Aug 20;11(8):
pubmed: 31434242
PLoS Biol. 2010 Jun 29;8(6):e1000412
pubmed: 20613859
IUBMB Life. 2007 Oct;59(10):628-633
pubmed: 17852568
J Infect Dis. 2007 Sep 15;196(6):954-62
pubmed: 17703428
Pharmaceuticals (Basel). 2009 Dec 01;2(3):134-149
pubmed: 27713230
Toxicol Appl Pharmacol. 2004 Nov 15;201(1):21-31
pubmed: 15519605
Lancet. 2017 Nov 25;390(10110):2397-2409
pubmed: 28673422
Mediators Inflamm. 2014;2014:902038
pubmed: 25276058
BMC Pharmacol Toxicol. 2021 Apr 7;22(1):19
pubmed: 33827703
Prog Neurobiol. 2010 Jun;91(2):152-71
pubmed: 19995590
Parasitol Int. 2014 Apr;63(2):417-26
pubmed: 24440762
Malawi Med J. 2015 Jun;27(2):45-50
pubmed: 26405511
Front Immunol. 2018 Apr 13;9:754
pubmed: 29706967
J Infect Dis. 2001 Jun 15;183(12):1794-800
pubmed: 11372033
Biochem Pharmacol. 2009 Dec 1;78(11):1391-400
pubmed: 19632207
Sci Rep. 2017 Aug 15;7(1):8253
pubmed: 28811612
PLoS Negl Trop Dis. 2012;6(10):e1857
pubmed: 23145191
BMJ Open. 2019 May 14;9(5):e029053
pubmed: 31092669
Methods. 2017 Aug 15;127:79-87
pubmed: 28636879
Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8892-7
pubmed: 9671775
Parasitol Int. 2008 Sep;57(3):325-33
pubmed: 18456544
Allergy Asthma Clin Immunol. 2016 Jan 22;12:4
pubmed: 26807135
Curr Rheumatol Rep. 2014 Feb;16(2):401
pubmed: 24390755
J Neurovirol. 2008 Oct;14(5):344-51
pubmed: 19016378
Anal Biochem. 1980 Jul 15;106(1):207-12
pubmed: 7416462
Rev Inst Med Trop Sao Paulo. 1992 Jan-Feb;34(1):9-13
pubmed: 1307413
Trends Parasitol. 2003 Nov;19(11):488-94
pubmed: 14580959
PLoS Negl Trop Dis. 2017 Jul 27;11(7):e0005642
pubmed: 28750004
Heliyon. 2020 Sep 14;6(9):e04917
pubmed: 32984611
Am J Trop Med Hyg. 2011 Feb;84(2):344-50
pubmed: 21292912
CMAJ. 2005 Feb 1;172(3):367-79
pubmed: 15684121
Medicines (Basel). 2015 Sep;2(3):157-185
pubmed: 26949700
Parasitol Int. 2019 Aug;71:106-120
pubmed: 30981893

Auteurs

Lynn Kitwan (L)

Department of Medical Microbiology Department, Jomo Kenyatta University of Agriculture and Technology (JKUAT), Nairobi, Kenya.

Celestine Makobe (C)

Department of Medical Microbiology Department, Jomo Kenyatta University of Agriculture and Technology (JKUAT), Nairobi, Kenya.

Raymond Mdachi (R)

Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.

Dawn Nyawira Maranga (DN)

Animal Science Department, Institute of Primate Research, Nairobi, 00502 Kenya.

Alfred Orina Isaac (AO)

Department of Pharmaceutical Sciences and Technology, Technical University of Kenya, Nairobi, Kenya.

James Nyabuga Nyariki (JN)

Department of Biochemistry and Biotechnology, Technical University of Kenya, Nairobi, Kenya.

Classifications MeSH