Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda.


Journal

African health sciences
ISSN: 1729-0503
Titre abrégé: Afr Health Sci
Pays: Uganda
ID NLM: 101149451

Informations de publication

Date de publication:
Sep 2022
Historique:
entrez: 13 3 2023
pubmed: 14 3 2023
medline: 15 3 2023
Statut: ppublish

Résumé

Invasive pulmonary aspergillosis is known to complicate the coronavirus diseases-2019 (COVID-19), especially those with critical illness. We investigated the baseline anti-Aspergillus antibody serostatus of patients with moderate-critical COVID-19 hospitalized at 3 COVID-19 Treatment Units in Uganda. All 46 tested patients, mean age 30, and 11% with underlying respiratory disease had a negative serum anti-Aspergillus IgM/IgG antibody immunochromatographic test on day 3 (mean) of symptom onset (range 1-26), but follow up specimens to assess seroconversion were not available.

Identifiants

pubmed: 36910368
doi: 10.4314/ahs.v22i3.54
pii: jAFHS.v22.i3.pg506
pmc: PMC9993298
doi:

Substances chimiques

Immunoglobulin G 0
Immunoglobulin M 0
Antibodies, Viral 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

506-511

Informations de copyright

© 2022 Bongomin F et al.

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Auteurs

Felix Bongomin (F)

Department of Medical Microbiology and Immunology, Gulu University Medical School, Gulu Uganda.

Richard Kwizera (R)

Translational research laboratory, Department of Research, Infectious Diseases Institute, College of Health Sciences, Makerere University, P.O Box 22418, Kampala, Uganda.

Emmanuel Mande (E)

Translational research laboratory, Department of Research, Infectious Diseases Institute, College of Health Sciences, Makerere University, P.O Box 22418, Kampala, Uganda.

Sharley Melissa Aloyo (SM)

Department of Immunology and Molecular Biology, Makerere University College of Health Sciences, Kampala, Uganda.

Beatrice Achan (B)

Department of Medical Microbiology, College of Health Sciences, Makerere University, Kampala, Uganda.

Martha Namusobya (M)

Department of Internal Medicine, Mulago National Referral Hospital, Kampala, Uganda.

Senai Goitom Sereke (SG)

Department of Radiology and Radiotherapy, College of Health Sciences, Makerere University, Kampala, Uganda.

Charles Batte (C)

Makerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda.

Sarah Kiguli (S)

Department of Pediatrics and Child Health, College of Health Sciences, Makerere University, Kampala, Uganda.

Joseph Baruch Baluku (JB)

Department of Internal Medicine, Mulago National Referral Hospital, Kampala, Uganda.
Directorate of Programs, Mildmay Uganda, Wakiso, Uganda.

Moses L Joloba (ML)

Department of Immunology and Molecular Biology, Makerere University College of Health Sciences, Kampala, Uganda.

Bruce J Kirenga (BJ)

Makerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda.

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Classifications MeSH