The effect of sodium thiosulfate on immune cell metabolism during porcine hemorrhage and resuscitation.

hemorrhagic shock hydrogen sulfide immunometabolism innate immunity metabolic flux analysis metabolic modeling mitochondrial respiration reactive oxygen species

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2023
Historique:
received: 16 12 2022
accepted: 13 02 2023
entrez: 13 3 2023
pubmed: 14 3 2023
medline: 15 3 2023
Statut: epublish

Résumé

Sodium thiosulfate (Na After 3 h of hemorrhage, anesthetized and surgically instrumented swine underwent resuscitation up to a maximum of 68 h. At 2 h of shock, animals randomly received vehicle or Na PBMCs showed significantly higher mitochondrial O In a porcine model of hemorrhage and resuscitation, Na

Identifiants

pubmed: 36911662
doi: 10.3389/fimmu.2023.1125594
pmc: PMC9996035
doi:

Substances chimiques

sodium thiosulfate HX1032V43M
Lipids 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1125594

Informations de copyright

Copyright © 2023 Wolfschmitt, Hogg, Vogt, Zink, Wachter, Hezel, Zhang, Hoffmann, Gröger, Hartmann, Gässler, Datzmann, Merz, Hellmann, Kranz, Calzia, Radermacher and Messerer.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer JB declared a past collaboration with the authors E-MW, MG and MH to the handling editor.

Références

J Leukoc Biol. 2017 Feb;101(2):599-611
pubmed: 27601627
Biochemistry. 1967 Jul;6(7):2227-47
pubmed: 6049456
J Cardiovasc Transl Res. 2018 Jun;11(3):246-258
pubmed: 29721767
Mol Metab. 2022 Mar;57:101424
pubmed: 34954109
J Mol Med (Berl). 2012 Dec;90(12):1391-406
pubmed: 23090009
Pharmacol Rev. 2017 Oct;69(4):497-564
pubmed: 28978633
J Exp Med. 2016 Jan 11;213(1):15-23
pubmed: 26694970
Crit Care Med. 2012 Jul;40(7):2157-67
pubmed: 22713217
Chem Biol Interact. 2017 Aug 25;274:24-34
pubmed: 28688941
J Evid Based Soc Work (2019). 2021 May-Jun;18(3):284-307
pubmed: 33131464
Front Immunol. 2015 Jan 22;6:1
pubmed: 25657648
Redox Biol. 2014 Jan 10;2:206-10
pubmed: 24494194
J Surg Res. 2015 Nov;199(1):197-210
pubmed: 25956183
Methods Mol Biol. 2018;1782:31-70
pubmed: 29850993
Cell Metab. 2018 Nov 6;28(5):706-720.e6
pubmed: 30122555
Crit Care. 2013 Jul 10;17(4):R129
pubmed: 23841996
Biotechnol Bioeng. 2002 Nov 20;80(4):477-9
pubmed: 12325156
Mol Biol Rep. 2022 Oct;49(10):9783-9795
pubmed: 35696048
J Biol Chem. 2021 Aug;297(2):100950
pubmed: 34252456
J Am Heart Assoc. 2015 Nov 06;4(11):
pubmed: 26546573
N Engl J Med. 2018 Jun 21;378(25):2376-2385
pubmed: 29924955
Thrombosis. 2010;2010:461238
pubmed: 22091368
Shock. 2011 Jan;35(1):67-73
pubmed: 20523266
Ann Emerg Med. 2017 Jun;69(6):718-725.e4
pubmed: 28041825
Biol Pharm Bull. 2012;35(7):1029-34
pubmed: 22791148
Ann Emerg Med. 2012 Jun;59(6):532-9
pubmed: 22387086
Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6663-6674
pubmed: 32139610
PLoS Med. 2017 Jul 5;14(7):e1002310
pubmed: 28678794
Curr Opin Biotechnol. 2015 Aug;34:189-201
pubmed: 25731751
Crit Care Med. 2016 May;44(5):e264-77
pubmed: 26588829
Anesthesiology. 2014 Dec;121(6):1248-57
pubmed: 25260144
Immunity. 2013 Apr 18;38(4):633-43
pubmed: 23601682
Br J Pharmacol. 2014 Apr;171(8):2099-122
pubmed: 23991830
Metab Eng. 2007 Jan;9(1):68-86
pubmed: 17088092
Methods Enzymol. 2014;542:369-89
pubmed: 24862276
Am J Physiol. 1998 May;274(5):E843-51
pubmed: 9612242
J Immunol. 2007 May 15;178(10):6573-80
pubmed: 17475888
Am J Physiol Regul Integr Comp Physiol. 2013 Sep 15;305(6):R592-603
pubmed: 23804280
J Biol Chem. 1955 Nov;217(1):395-407
pubmed: 13271403
NMR Biomed. 2019 Jun;32(6):e4096
pubmed: 30924572
J Trauma. 2008 Jul;65(1):183-8
pubmed: 18580516
Int J Surg Protoc. 2018 Apr 17;9:15-19
pubmed: 31851733
Anal Chem. 2007 Oct 1;79(19):7554-9
pubmed: 17822305
Am J Physiol. 1997 Jun;272(6 Pt 1):C2049-62
pubmed: 9227434
J Surg Res. 2012 Jul;176(1):210-9
pubmed: 21962736
Pharmacol Res. 2020 Jan;151:104536
pubmed: 31734346
Curr Metabolomics. 2018;6(3):176-187
pubmed: 31745452
Science. 2013 Oct 11;342(6155):1242454
pubmed: 24115444
Cell. 2016 Jun 30;166(1):63-76
pubmed: 27293185
Ann Emerg Med. 2010 Apr;55(4):345-51
pubmed: 19944487
Inflamm Res. 2008 Nov;57(11):512-8
pubmed: 19109743
Nat Rev Immunol. 2016 Sep;16(9):553-65
pubmed: 27396447
Shock. 2021 Mar 1;55(3):407-417
pubmed: 32826816
Annu Rev Immunol. 2018 Apr 26;36:461-488
pubmed: 29677474
Shock. 2019 Aug;52(2):230-239
pubmed: 29927788
J Theor Biol. 2008 Sep 21;254(2):466-75
pubmed: 18603266
Crit Care. 2010;14(5):R165
pubmed: 20836847
Bioinformatics. 2013 Jan 1;29(1):143-5
pubmed: 23110970
Metab Eng. 2001 Jul;3(3):195-206
pubmed: 11461141
Nitric Oxide. 2014 Sep 15;41:79-84
pubmed: 24963794
Redox Biol. 2021 Jan;38:101772
pubmed: 33137711
Nat Rev Immunol. 2005 Nov;5(11):844-52
pubmed: 16239903
FASEB J. 2007 Jun;21(8):1699-706
pubmed: 17314140
Br J Pharmacol. 2004 Dec;143(7):881-9
pubmed: 15504752
Crit Care. 2012 Oct 02;16(5):R178
pubmed: 23031430
J Pathol. 2016 Jan;238(2):321-32
pubmed: 26467985
Int J Mol Sci. 2021 Jun 16;22(12):
pubmed: 34208631
Biomolecules. 2022 Feb 24;12(3):
pubmed: 35327553
Sci Rep. 2017 Aug 10;7(1):7743
pubmed: 28798364
Front Immunol. 2022 Jun 16;13:901005
pubmed: 35784322
Br J Pharmacol. 2014 Apr;171(8):2123-46
pubmed: 23991749

Auteurs

Eva-Maria Wolfschmitt (EM)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Melanie Hogg (M)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Josef Albert Vogt (JA)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Fabian Zink (F)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Ulrich Wachter (U)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Felix Hezel (F)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Xiaomin Zhang (X)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Andrea Hoffmann (A)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Michael Gröger (M)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Clair Hartmann (C)

Clinic for Anesthesia and Intensive Care, University Hospital Ulm, Ulm, Germany.

Holger Gässler (H)

Department of Anaesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Therapy, Federal Armed Forces Hospital Ulm, Ulm, Germany.

Thomas Datzmann (T)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Clinic for Anesthesia and Intensive Care, University Hospital Ulm, Ulm, Germany.

Tamara Merz (T)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Andreas Hellmann (A)

Institute of Analytical and Bioanalytical Chemistry, Ulm University, Ulm, Germany.

Christine Kranz (C)

Institute of Analytical and Bioanalytical Chemistry, Ulm University, Ulm, Germany.

Enrico Calzia (E)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

Peter Radermacher (P)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.

David Alexander Christian Messerer (DAC)

Institute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Clinic for Anesthesia and Intensive Care, University Hospital Ulm, Ulm, Germany.
Department of Transfusion Medicine and Hemostaseology, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany.

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