Mushroom consumption and risk of gastric cancer: a pooled analysis within the stomach cancer pooling project and a combined meta-analysis with other observational studies.


Journal

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)
ISSN: 1473-5709
Titre abrégé: Eur J Cancer Prev
Pays: England
ID NLM: 9300837

Informations de publication

Date de publication:
01 05 2023
Historique:
pmc-release: 01 05 2024
medline: 4 4 2023
pubmed: 14 3 2023
entrez: 13 3 2023
Statut: ppublish

Résumé

Edible mushrooms have high concentrations of vitamins and minerals. They are considered 'functional foods' for their disease-prevention properties. Mushroom consumption may reduce the risk of gastric cancer, the fifth most common cancer worldwide. We investigated the association between mushroom consumption and gastric cancer risk in a pooled analysis within the Stomach Cancer Pooling (StoP) Project and in a meta-analysis that also included previously published studies. A total of 3900 gastric cancer cases and 7792 controls from 11 studies were included in the StoP analysis. Mushroom consumption was measured using food frequency questionnaires. Higher mushroom consumption was associated with a lower risk of gastric cancer [relative risk (RR) for the highest vs. lowest consumption categories, 0.82; 95% confidence interval (CI), 0.71-0.95]. The corresponding RRs were 0.59 (95% CI, 0.26-1.33) in a meta-analysis of four previously published studies and 0.77 for all studies combined (95% CI, 0.63-0.95; n = 15 studies). In geographic subgroup analysis, the pooled risk in Western Pacific countries was (RR, 0.59; 95% CI, 0.40-0.87; n = 6). The stronger effect in Asian countries may reflect high level of antioxidants in mushroom species consumed in Asia.

Identifiants

pubmed: 36912187
doi: 10.1097/CEJ.0000000000000754
pii: 00008469-202305000-00004
pmc: PMC10073218
mid: NIHMS1782981
doi:

Types de publication

Meta-Analysis Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

222-228

Subventions

Organisme : NIDA NIH HHS
ID : P50 DA036107
Pays : United States

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

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Auteurs

Djibril M Ba (DM)

Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.

Paddy Ssentongo (P)

Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.

Claudio Pelucchi (C)

Department of Clinical Sciences and Community Health, University of Milan, Milan.

Eva Negri (E)

Department of Clinical Sciences and Community Health, University of Milan, Milan.
Pegaso Online University, Naples.

Domenico Palli (D)

Cancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network, ISPRO, Florence, Italy.

Monica Ferraroni (M)

Department of Clinical Sciences and Community Health, University of Milan, Milan.

Zuo-Feng Zhang (ZF)

Department of Epidemiology, UCLA Fielding School of Public Health and Jonsson Comprehensive Cancer Center, Los Angeles, California, USA.

Guo-Pei Yu (GP)

Medical Informatics Center, Peking University, Peking, China.

Shoichiro Tsugane (S)

Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center.
National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.

Akihisa Hidaka (A)

Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center.

Gerson Shigueaki Hamada (GS)

Nikkei Disease Prevention Center, São Paulo, Brazil.

David Zaridze (D)

Department of Epidemiology and Prevention, Russian N.N. Blokhin Cancer Research Center, Moscow, Russia.

Dmitry Maximovich (D)

Department of Epidemiology and Prevention, Russian N.N. Blokhin Cancer Research Center, Moscow, Russia.

Mireia Obón-Santacana (M)

Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid.
Unit of Biomarkers and Suceptibility (UBS), Oncology Data Analytics Program (ODAP), Catalan Institute of Oncology (ICO), L'Hospitalet del Llobregat.
ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona.

Laura Álvarez-Álvarez (L)

Group of Investigation in Interactions Gene-Environment and Health (GIIGAS), Institute of Biomedicine (IBIOMED), University of León, León.

Jesus Vioque (J)

Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid.
Instituto de Investigación Sanitaria y Biomédica de Alicante, Universidad Miguel Hernandez (ISABIAL-UMH), Alicante, Spain.

Manoli Garcia de la Hera (M)

Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid.
Instituto de Investigación Sanitaria y Biomédica de Alicante, Universidad Miguel Hernandez (ISABIAL-UMH), Alicante, Spain.

Lizbeth López-Carrillo (L)

Mexico National Institute of Public Health, Morelos.

Malaquias López-Cervantes (M)

Facultad de Medicina, UNAM, Coyoacán, Mexico.

Lina Mu (L)

Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York, USA.

Areti Lagiou (A)

Department of Public and Community Health, School of Public Health, University of West Attica.

Pagona Lagiou (P)

Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

Paolo Boffetta (P)

Stony Brook Cancer Center, Stony Brook University, Stony Brook, New York, USA.
Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Maria Constanza Camargo (MC)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.

Maria Paula Curado (MP)

Centro Internacional de Pesquisa, A. C. Camargo Cancer Center, São Paulo, Brazil.

Nuno Lunet (N)

EPIUnit - Instituto de Saúde Pública da Universidade do Porto.
Laboratório para a Investigação Integrativa e Translacional em Saúde Populacional (ITR).
Departamento de Ciências da Saúde Pública e Forenses e Educação Médica, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.

Carlo La Vecchia (C)

Department of Clinical Sciences and Community Health, University of Milan, Milan.

Joshua Muscat (J)

Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.

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