Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016-2018.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2023
Historique:
received: 30 05 2022
accepted: 19 02 2023
entrez: 15 3 2023
pubmed: 16 3 2023
medline: 21 3 2023
Statut: epublish

Résumé

We assessed progress in HIV viral load (VL) scale up across seven sub-Saharan African (SSA) countries and discussed challenges and strategies for improving VL coverage among patients on anti-retroviral therapy (ART). A retrospective review of VL testing was conducted in Côte d'Ivoire, Kenya, Lesotho, Malawi, Namibia, Tanzania, and Uganda from January 2016 through June 2018. Data were collected and included the cumulative number of ART patients, number of patients with ≥ 1 VL test result (within the preceding 12 months), the percent of VL test results indicating viral suppression, and the mean turnaround time for VL testing. Between 2016 and 2018, the proportion of PLHIV on ART in all 7 countries increased (range 5.7%-50.2%). During the same time period, the cumulative number of patients with one or more VL test increased from 22,996 to 917,980. Overall, viral suppression rates exceeded 85% for all countries except for Côte d'Ivoire at 78% by June 2018. Reported turnaround times for VL testing results improved in 5 out of 7 countries by between 5.4 days and 27.5 days. These data demonstrate that remarkable progress has been made in the scale-up of HIV VL testing in the seven SSA countries.

Identifiants

pubmed: 36920918
doi: 10.1371/journal.pone.0282652
pii: PONE-D-22-15612
pmc: PMC10016655
doi:

Substances chimiques

Anti-HIV Agents 0

Types de publication

Journal Article Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0282652

Subventions

Organisme : PEPFAR
Pays : United States

Informations de copyright

Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

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Auteurs

Peter N Fonjungo (PN)

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Shirley Lecher (S)

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Clement Zeh (C)

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Erin Rottinghaus (E)

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Helen Chun (H)

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Christiane Adje-Toure (C)

Division of Global HIV and TB, Center for Global Health, CDC, Abidjan, Côte d'Ivoire.

Spencer Lloyd (S)

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Jane W Mwangi (JW)

Division of Global HIV and TB, Center for Global Health, CDC, Nairobi, Kenya.

Michael Mwasekaga (M)

Division of Global HIV and TB, Center for Global Health, CDC, Dar es Salaam, Tanzania.

Yohannes Mengistu Eshete (YM)

Division of Global HIV and TB, Center for Global Health, CDC, Maseru, Lesotho.

Rituparna Pati (R)

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Tsietso Mots'oane (T)

Laboratory Services, Ministry of Health, Maseru, Lesotho.

Kiren Mitruka (K)

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Anita Beukes (A)

Namibia Institute of Pathology, Windhoek, Namibia.

Christina Mwangi (C)

Division of Global HIV and TB, Center for Global Health, CDC, Kampala, Uganda.

Nancy Bowen (N)

Ministry of Health, Nairobi, Kenya.

Ndapewa Hamunime (N)

Ministry of Health and Social Services, Windhoek, Namibia.

Rachel S Beard (RS)

Division of Global HIV and TB, Center for Global Health, CDC, Windhoek, Namibia.

Anyelwisye Kabuje (A)

Ministry of Health, Dar es Salaam, Tanzania.

Susan Nabadda (S)

Central Public Health Laboratories, Kampala, Uganda.

Andrew F Auld (AF)

Division of Global HIV and TB, Center for Global Health, CDC, Lilongwe, Malawi.

Shirish Balachandra (S)

Division of Global HIV and TB, Center for Global Health, CDC, Abidjan, Côte d'Ivoire.

Innocent Zungu (I)

Division of Global HIV and TB, Center for Global Health, CDC, Lilongwe, Malawi.

James Kandulu (J)

Ministry of Health, Lilongwe, Malawi.

George Alemnji (G)

Office of the Global AIDS Coordinator and Health Diplomacy, U.S. Department of State, Washington, DC, United States of America.

Eboi Ehui (E)

Ministry of Health, Abidjan, Côte D'Ivoire.

Heather Alexander (H)

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Dennis Ellenberger (D)

Division of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

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