COVID-19 vaccine hesitancy and its drivers: An empirical study of the vaccine hesitant group in Malaysia.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2023
Historique:
received: 12 08 2022
accepted: 16 02 2023
entrez: 15 3 2023
pubmed: 16 3 2023
medline: 21 3 2023
Statut: epublish

Résumé

Sporadic outbreaks of COVID-19 remain a threat to public healthcare, especially if vaccination levels do not improve. As Malaysia begins its transition into the endemic phase, it is essential to identify the key determinants of COVID-19 vaccination intention amongst the pockets of the population who are still hesitant. Therefore, focusing on a sample of individuals who did not register for the COVID-19 vaccination, the current study integrated two widely used frameworks in the public health domain-the health belief model (HBM) and the theory of reasoned action (TRA)-to examine the inter-relationships of the predictors of vaccination intention amongst these individuals. Primary data from 117 respondents who did not register for the COVID-19 vaccination were collected using self-administered questionnaires to capture predictors of vaccination intention amongst individuals in a Malaysian context. The partial least squares structural equation modeling (PLS-SEM) technique was used to analyze the data. Subjective norms and attitude play key mediating roles between the HBM factors and vaccination intention amongst the unregistered respondents. In particular, subjective norms mediate the relationship between cues to action and vaccination intention, highlighting the significance of important others to influence unregistered individuals who are already exposed to information from mass media and interpersonal discussions regarding vaccines. Trust, perceived susceptibility, and perceived benefits indirectly influence vaccination intention through attitude, indicating that one's attitude is vital in promoting behavioral change. This study showed that the behavioral factors could help understand the reasons for vaccine refusal or acceptance, and shape and improve health interventions, particularly among the vaccine-hesitant group in a developing country. Therefore, policymakers and key stakeholders can develop effective strategies or interventions to encourage vaccination amongst the unvaccinated for future health pandemics by targeting subjective norms and attitude.

Sections du résumé

BACKGROUND
Sporadic outbreaks of COVID-19 remain a threat to public healthcare, especially if vaccination levels do not improve. As Malaysia begins its transition into the endemic phase, it is essential to identify the key determinants of COVID-19 vaccination intention amongst the pockets of the population who are still hesitant. Therefore, focusing on a sample of individuals who did not register for the COVID-19 vaccination, the current study integrated two widely used frameworks in the public health domain-the health belief model (HBM) and the theory of reasoned action (TRA)-to examine the inter-relationships of the predictors of vaccination intention amongst these individuals.
METHODOLOGY
Primary data from 117 respondents who did not register for the COVID-19 vaccination were collected using self-administered questionnaires to capture predictors of vaccination intention amongst individuals in a Malaysian context. The partial least squares structural equation modeling (PLS-SEM) technique was used to analyze the data.
RESULTS
Subjective norms and attitude play key mediating roles between the HBM factors and vaccination intention amongst the unregistered respondents. In particular, subjective norms mediate the relationship between cues to action and vaccination intention, highlighting the significance of important others to influence unregistered individuals who are already exposed to information from mass media and interpersonal discussions regarding vaccines. Trust, perceived susceptibility, and perceived benefits indirectly influence vaccination intention through attitude, indicating that one's attitude is vital in promoting behavioral change.
CONCLUSION
This study showed that the behavioral factors could help understand the reasons for vaccine refusal or acceptance, and shape and improve health interventions, particularly among the vaccine-hesitant group in a developing country. Therefore, policymakers and key stakeholders can develop effective strategies or interventions to encourage vaccination amongst the unvaccinated for future health pandemics by targeting subjective norms and attitude.

Identifiants

pubmed: 36920970
doi: 10.1371/journal.pone.0282520
pii: PONE-D-22-22626
pmc: PMC10016727
doi:

Substances chimiques

COVID-19 Vaccines 0

Banques de données

figshare
['10.6084/m9.figshare.22132067.v1']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0282520

Informations de copyright

Copyright: © 2023 Vaithilingam et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

Hum Vaccin Immunother. 2021 Jun 3;17(6):1612-1621
pubmed: 33242386
Lancet. 2021 Dec 4;398(10316):2093-2100
pubmed: 34756184
Innov Pharm. 2012;3(2):1-11
pubmed: 22844651
BMC Public Health. 2011 Jul 19;11:575
pubmed: 21771296
Vaccine. 2015 Aug 14;33(34):4161-4
pubmed: 25896383
Vaccine. 2015 Aug 14;33(34):4176-9
pubmed: 25896376
Patient Educ Couns. 2021 Aug;104(8):1878-1886
pubmed: 33632632
Vaccines (Basel). 2021 Oct 09;9(10):
pubmed: 34696264
PLoS One. 2021 Aug 13;16(8):e0256110
pubmed: 34388202
N Engl J Med. 2022 Mar 10;386(10):933-941
pubmed: 35020982
J Public Health (Oxf). 2021 Sep 22;43(3):e529-e530
pubmed: 34080617
Health Promot Int. 2022 Feb 17;37(1):
pubmed: 33928389
Ecohealth. 2021 Mar;18(1):44-60
pubmed: 34086129
Hum Vaccin Immunother. 2020 Sep 1;16(9):2204-2214
pubmed: 32730103
Vaccine. 2021 Nov 26;39(48):6984-6989
pubmed: 34763949
Patient Educ Couns. 2022 Feb;105(2):277-283
pubmed: 34565643
J Health Commun. 2020 Oct 2;25(10):819-826
pubmed: 33719874
N Engl J Med. 2022 Apr 21;386(16):1532-1546
pubmed: 35249272
Vaccine. 2022 Apr 6;40(16):2442-2456
pubmed: 35305823
PLoS One. 2022 May 23;17(5):e0268926
pubmed: 35604921
Soc Sci Med. 2017 Nov;193:70-79
pubmed: 29028558
Eur J Health Econ. 2020 Sep;21(7):977-982
pubmed: 32591957
Lancet Reg Health Eur. 2021 Feb;1:100012
pubmed: 33954296
J Health Commun. 2015;20(1):69-79
pubmed: 24870976
Health Aff (Millwood). 2011 Jun;30(6):1151-9
pubmed: 21653969
Nurs Res. 1986 Nov-Dec;35(6):382-5
pubmed: 3640358
BMC Public Health. 2021 Jun 12;21(1):1129
pubmed: 34118897
Lancet Infect Dis. 2021 May;21(5):e110
pubmed: 32941786
EClinicalMedicine. 2022 Mar 05;45:101326
pubmed: 35261970
Vaccine. 2022 Mar 18;40(13):2020-2027
pubmed: 35216840

Auteurs

Santha Vaithilingam (S)

Sunway Institute for Global Strategy and Competitiveness, Sunway University, Selangor, Malaysia.

Li-Ann Hwang (LA)

Department of Econometrics and Business Statistics, School of Business, Monash University, Selangor, Malaysia.

Mahendhiran Nair (M)

Sunway Institute for Global Strategy and Competitiveness, Sunway University, Selangor, Malaysia.

Jason Wei Jian Ng (JWJ)

Department of Pure and Applied Mathematics, School of Mathematical Sciences, Sunway University, Selangor, Malaysia.

Pervaiz Ahmed (P)

Sunway Institute for Global Strategy and Competitiveness, Sunway University, Selangor, Malaysia.

Kamarul Imran Musa (KI)

Department of Community Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH