Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies.

Signal confounding noise observational studies postrandomization bias randomized controlled trials regression

Journal

Indian journal of psychological medicine
ISSN: 0253-7176
Titre abrégé: Indian J Psychol Med
Pays: United States
ID NLM: 7910727

Informations de publication

Date de publication:
Mar 2023
Historique:
entrez: 17 3 2023
pubmed: 18 3 2023
medline: 18 3 2023
Statut: ppublish

Résumé

The previous article in this series explained basic concepts related to statistical signals and statistical noise in research. This article explains statistical noise in the context of randomized controlled trials (RCTs) and observational studies and offers suggestions on how noise in such studies may be reduced so as to better detect and understand the signal. Postrandomization bias related to RCTs and confounding in observational studies are discussed. Examples are provided to facilitate understanding.

Identifiants

pubmed: 36925488
doi: 10.1177/02537176221149162
pii: 10.1177_02537176221149162
pmc: PMC10011845
doi:

Types de publication

Journal Article

Langues

eng

Pagination

198-200

Informations de copyright

© 2023 The Author(s).

Déclaration de conflit d'intérêts

The author declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Références

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Auteurs

Chittaranjan Andrade (C)

Dept. of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.

Classifications MeSH