A multimodal analysis of genomic and RNA splicing features in myeloid malignancies.

Bioinformatics Cancer Omics

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
17 Mar 2023
Historique:
received: 02 11 2022
revised: 12 01 2023
accepted: 15 02 2023
entrez: 17 3 2023
pubmed: 18 3 2023
medline: 18 3 2023
Statut: epublish

Résumé

RNA splicing dysfunctions are more widespread than what is believed by only estimating the effects resulting by splicing factor mutations (SF

Identifiants

pubmed: 36926651
doi: 10.1016/j.isci.2023.106238
pii: S2589-0042(23)00315-2
pmc: PMC10011742
doi:

Types de publication

Journal Article

Langues

eng

Pagination

106238

Informations de copyright

© 2023 The Author(s).

Déclaration de conflit d'intérêts

The authors declare no competing interests.

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Auteurs

Arda Durmaz (A)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Systems Biology and Bioinformatics Department, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

Carmelo Gurnari (C)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Rome, Italy.

Courtney E Hershberger (CE)

Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.

Simona Pagliuca (S)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Department of Clinical Hematology, CHRU de Nancy, Nancy, France.

Noah Daniels (N)

Department of Cardiovascular & Metabolic Sciences, Cleveland Clinic, Cleveland, OH, USA.

Hassan Awada (H)

Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

Hussein Awada (H)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

Vera Adema (V)

MD Anderson Cancer Center, Houston, TX, USA.

Minako Mori (M)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

Ben Ponvilawan (B)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

Yasuo Kubota (Y)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

Tariq Kewan (T)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

Waled S Bahaj (WS)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

John Barnard (J)

Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA.

Jacob Scott (J)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Systems Biology and Bioinformatics Department, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

Richard A Padgett (RA)

Department of Cardiovascular & Metabolic Sciences, Cleveland Clinic, Cleveland, OH, USA.

Torsten Haferlach (T)

MLL Munich Leukemia Laboratory, Munich, Germany.

Jaroslaw P Maciejewski (JP)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

Valeria Visconte (V)

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

Classifications MeSH