COVID-19-induced transaminitis and hyperbilirubinemia: Presentation and outcomes.
COVID-19
Hyperbilirubinemia
Liver injury
Pathophysiology
SARS-CoV-2
Transaminases
Journal
World journal of gastroenterology
ISSN: 2219-2840
Titre abrégé: World J Gastroenterol
Pays: United States
ID NLM: 100883448
Informations de publication
Date de publication:
21 Feb 2023
21 Feb 2023
Historique:
received:
10
09
2022
revised:
29
12
2022
accepted:
13
02
2023
entrez:
17
3
2023
pubmed:
18
3
2023
medline:
21
3
2023
Statut:
ppublish
Résumé
The risk of liver injury in patients with coronavirus disease 2019 (COVID-19) infection is quite evident. Furthermore, liver function test abnormalities are still detected in COVID-19 patients despite the development of antivirals and the availability of several types of vaccines. This editorial describes liver involvement during COVID-19 infection in patients with or without preexisting liver injury, such as chronic liver disease, to elucidate COVID-19-induced liver function abnormalities and their severity, pathophysiology, clinical manifestations, and clinical and laboratory outcomes. We also discuss the effect of vaccination against COVID-19 to better understand host factors, such as age, gender, and race, on the incidence and severity of liver dysfunction at initial presentation and during the illness. Finally, we summarize the results of relevant meta-analyses published to date and highlight the importance of adequate liver function monitoring in the current climate of the overwhelming COVID-19 pandemic.
Identifiants
pubmed: 36926664
doi: 10.3748/wjg.v29.i7.1123
pmc: PMC10011958
doi:
Types de publication
Editorial
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1123-1130Informations de copyright
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
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