Cholesteric liquid crystal biosensor platform with image analysis for rapid detection of COVID-19.
COVID-19
biosensor
cholesteric liquid crystal
diagnosis
spike protein
Journal
Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513
Informations de publication
Date de publication:
2023
2023
Historique:
received:
20
01
2023
accepted:
17
02
2023
entrez:
17
3
2023
pubmed:
18
3
2023
medline:
18
3
2023
Statut:
epublish
Résumé
Rapid and low-cost diagnosis of coronavirus disease 2019 (COVID-19) is essential to identify infected subjects, particularly asymptomatic cases, primarily to arrest the spread of the disease through local transmission. Antibody-based chromatographic serological tests, as an alternative to the RT-PCR technique, offer only limited help due to high false positives. We propose to exploit our cholesteric liquid crystal biosensor platform for one-step, wash-free, rapid detection of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus directly with minimal sample pre-processing. As mentioned above, cholesteric liquid crystals are an effective and innovative approach to healthcare as a rapid test for the diagnosis of COVID-19 and other diseases.
Identifiants
pubmed: 36926691
doi: 10.3389/fbioe.2023.1148446
pii: 1148446
pmc: PMC10011469
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1148446Informations de copyright
Copyright © 2023 Lin, Chung, Chuang, Wang, Lai, Hsu, Lin and Hsiao.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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