A cryptic clue to neurodegeneration?

Oligonucleotides, Antisense / therapeutic use Neurons / physiology Nerve Regeneration / genetics Alternative Splicing / genetics TDP-43 Proteinopathies / therapy Humans Animals Mice

Journal

Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511

Informations de publication

Date de publication:
17 03 2023
Historique:
entrez: 17 3 2023
pubmed: 18 3 2023
medline: 21 3 2023
Statut: ppublish

Résumé

Antisense oligonucleotides rescue cryptic RNA splicing and neuron regeneration.

Identifiants

DOI: 10.1126/science.adg8501 PMID: 36927030
pubmed: 36927030
doi: 10.1126/science.adg8501
doi:

Substances chimiques

Oligonucleotides, Antisense 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1090-1091

Auteurs

Niamh O'Brien (N)

UK Dementia Research Institute at King's College London, London, UK.
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, Camberwell, London, UK.

Sarah Mizielinska (S)

UK Dementia Research Institute at King's College London, London, UK.
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, Camberwell, London, UK.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Sondes moléculaires › Sondes d'acide nucléique › Éléments antisens (génétique) › Oligonucléotides antisens › A cryptic clue to neurodegeneration?
questionsmedicales.fr › Cellules › Neurones › A cryptic clue to neurodegeneration?
questionsmedicales.fr › Phénomènes biologiques › Régénération › Régénération nerveuse › A cryptic clue to neurodegeneration?
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Maturation post-transcriptionnelle des ARN › Épissage des ARN › Épissage alternatif › A cryptic clue to neurodegeneration?
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles de l'homéostasie des protéines › Protéinopathies TDP-43 › A cryptic clue to neurodegeneration?
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A cryptic clue to neurodegeneration?
questionsmedicales.fr › Eucaryotes › Animaux › A cryptic clue to neurodegeneration?
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A cryptic clue to neurodegeneration?