Effects of overexpression of histone H3K9me3 demethylase on development of porcine cloned embryos.

Swine / genetics Animals Histone Demethylases / metabolism Histones / genetics Nuclear Transfer Techniques Embryonic Development / genetics Blastocyst / metabolism RNA, Messenger / metabolism Cloning, Organism
H3K9me3 KDM4A KDM4D cloning embryo pig

Journal

Yi chuan = Hereditas
ISSN: 0253-9772
Titre abrégé: Yi Chuan
Pays: China
ID NLM: 9436478

Informations de publication

Date de publication:
20 Jan 2023
Historique:
entrez: 17 3 2023
pubmed: 18 3 2023
medline: 21 3 2023
Statut: ppublish

Résumé

The abnormal modification of histone is an important factor restricting development of porcine cloned embryos. Overexpression of histone H3K9me3 demethylase KDM4 family can effectively improve the developmental efficiency of cloned embryos. In order to explore the effects of overexpression of H3K9me3 demethylase on the development of porcine cloned embryos, 组蛋白异常修饰是克隆胚胎发育的重要制约因素，组蛋白H3K9me3去甲基化酶KDM4家族的过表达可以有效提高克隆胚胎的发育效率。为探究过表达H3K9me3去甲基化酶对猪克隆胚胎发育的影响，本研究在猪克隆胚胎1-细胞期和2-细胞期分别注射

Autres résumés

Type: Publisher (chi)
组蛋白异常修饰是克隆胚胎发育的重要制约因素，组蛋白H3K9me3去甲基化酶KDM4家族的过表达可以有效提高克隆胚胎的发育效率。为探究过表达H3K9me3去甲基化酶对猪克隆胚胎发育的影响，本研究在猪克隆胚胎1-细胞期和2-细胞期分别注射

Identifiants

DOI: 10.16288/j.yczz.22-244 PMID: 36927639
pubmed: 36927639
pii: 22-244
doi: 10.16288/j.yczz.22-244
doi:

Substances chimiques

Histone Demethylases EC 1.14.11.-
Histones 0
RNA, Messenger 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

67-77

Auteurs

Ya-Nan Li (YN)

1. National Engineering Research Center for Breeding Swine Industry, College of Animal Science of South China Agricultural University, Guangzhou 510642, China.
2. National & Local Joint Engineering Research Center for Breeding Animal Industry, Guangzhou 510642, China.
3. Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding, Guangzhou 510642, China.

Xian-Jun Zhang (XJ)

1. National Engineering Research Center for Breeding Swine Industry, College of Animal Science of South China Agricultural University, Guangzhou 510642, China.
2. National & Local Joint Engineering Research Center for Breeding Animal Industry, Guangzhou 510642, China.
3. Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding, Guangzhou 510642, China.

Ning Zhang (N)

1. National Engineering Research Center for Breeding Swine Industry, College of Animal Science of South China Agricultural University, Guangzhou 510642, China.
2. National & Local Joint Engineering Research Center for Breeding Animal Industry, Guangzhou 510642, China.
3. Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding, Guangzhou 510642, China.

Ya-Lin Liang (YL)

1. National Engineering Research Center for Breeding Swine Industry, College of Animal Science of South China Agricultural University, Guangzhou 510642, China.
2. National & Local Joint Engineering Research Center for Breeding Animal Industry, Guangzhou 510642, China.
3. Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding, Guangzhou 510642, China.

Yu-Xing Zhang (YX)

1. National Engineering Research Center for Breeding Swine Industry, College of Animal Science of South China Agricultural University, Guangzhou 510642, China.
2. National & Local Joint Engineering Research Center for Breeding Animal Industry, Guangzhou 510642, China.
3. Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding, Guangzhou 510642, China.

Hua-Xing Zhao (HX)

1. National Engineering Research Center for Breeding Swine Industry, College of Animal Science of South China Agricultural University, Guangzhou 510642, China.
2. National & Local Joint Engineering Research Center for Breeding Animal Industry, Guangzhou 510642, China.
3. Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding, Guangzhou 510642, China.

Zi-Cong Li (ZC)

1. National Engineering Research Center for Breeding Swine Industry, College of Animal Science of South China Agricultural University, Guangzhou 510642, China.
2. National & Local Joint Engineering Research Center for Breeding Animal Industry, Guangzhou 510642, China.
3. Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding, Guangzhou 510642, China.

Si-Xiu Huang (SX)

1. National Engineering Research Center for Breeding Swine Industry, College of Animal Science of South China Agricultural University, Guangzhou 510642, China.
2. National & Local Joint Engineering Research Center for Breeding Animal Industry, Guangzhou 510642, China.
3. Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding, Guangzhou 510642, China.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › Effects of overexpression of histone H3K9me3...
questionsmedicales.fr › Eucaryotes › Animaux › Effects of overexpression of histone H3K9me3...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Oxidoreductases acting on CH-NH group donors › Oxidoreductases, (N-demethylating) › Histone Demethylases › Effects of overexpression of histone H3K9me3...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Histone › Effects of overexpression of histone H3K9me3...
questionsmedicales.fr › Techniques d'investigation › Techniques de reproduction › Techniques de transfert nucléaire › Effects of overexpression of histone H3K9me3...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Développement embryonnaire et foetal › Développement embryonnaire › Effects of overexpression of histone H3K9me3...
questionsmedicales.fr › Structures de l'embryon › Embryon de mammifère › Blastocyste › Effects of overexpression of histone H3K9me3...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN messager › Effects of overexpression of histone H3K9me3...
questionsmedicales.fr › Techniques d'investigation › Techniques de reproduction › Clonage d'organisme › Effects of overexpression of histone H3K9me3...