New transperineal ultrasound-guided biopsy for men in whom PSA is increasing after Miles' operation.

Biopsy outcomes Biopsy techniques Miles’ operation Prostate cancer Transperineal US

Journal

Insights into imaging
ISSN: 1869-4101
Titre abrégé: Insights Imaging
Pays: Germany
ID NLM: 101532453

Informations de publication

Date de publication:
16 Mar 2023
Historique:
received: 21 09 2022
accepted: 04 02 2023
entrez: 17 3 2023
pubmed: 18 3 2023
medline: 18 3 2023
Statut: epublish

Résumé

Currently, a prostate biopsy is guided by transrectal ultrasound (US) alone. However, this biopsy cannot be performed in men without an anus. The aim of this study was to show the outcomes of a new transperineal US (TPUS)-guided biopsy technique in patients who underwent Miles' operation. Between April 2009 and March 2022, TPUS-guided biopsy was consecutively conducted in 9 patients (median, 71 years; range, 61-78 years) with high prostate-specific antigen values (22.60 ng/mL; 6.19-69.7 ng/mL). Their anuses were all removed due to rectal cancer. TPUS-guided biopsy was performed according to information on prostate magnetic resonance imaging. The technical success rate, cancer detection rate, and complication rate were recorded. Tumor sizes were compared between benign and cancer groups using an unpaired t-test with Welch's correction. The new TPUS-guided biopsy was successfully performed in all patients. Cancer was detected in 77.8% (7/9) of the patients. These were all categorized as PI-RADS 5. Among them, the detection rate of significant cancer (Gleason score 7 or higher) was 66.7% (6/9). The median tumor size was 2.4 cm (1.7-3.1 cm). However, two patients were diagnosed with benign tissue with PI-RADS 3 or PI-RADS 4. Their median tumor size was 1.0 cm (0.8-1.2 cm). There was significant difference between the cancer and benign groups (p = 0.037) in terms of tumor size. Neither post-biopsy bleeding nor infections occurred. New TPUS-guided biopsy technique may contribute to detecting large PI-RADS 5 prostate cancer in men after Miles' operation.

Identifiants

pubmed: 36929129
doi: 10.1186/s13244-023-01384-y
pii: 10.1186/s13244-023-01384-y
pmc: PMC10020382
doi:

Types de publication

Journal Article

Langues

eng

Pagination

42

Informations de copyright

© 2023. The Author(s).

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Auteurs

Byung Kwan Park (BK)

Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Dong, Gangnam-Ku, Seoul, 06351, Republic of Korea. rapark@skku.edu.

Jae Hoon Chung (JH)

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Wan Song (W)

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Minyong Kang (M)

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Hyun Hwan Sung (HH)

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Hwang Gyun Jeon (HG)

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Byong Chang Jeong (BC)

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Seong Il Seo (SI)

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Seong Soo Jeon (SS)

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Hyun Moo Lee (HM)

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Ghee Young Kwon (GY)

Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Classifications MeSH