Current and Emerging Techniques in Neuroimaging of Sport-Related Concussion.
Journal
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
ISSN: 1537-1603
Titre abrégé: J Clin Neurophysiol
Pays: United States
ID NLM: 8506708
Informations de publication
Date de publication:
01 Jul 2023
01 Jul 2023
Historique:
pmc-release:
01
07
2024
medline:
5
7
2023
pubmed:
18
3
2023
entrez:
17
3
2023
Statut:
ppublish
Résumé
Sport-related concussion (SRC) affects an estimated 1.6 to 3.8 million Americans each year. Sport-related concussion results from biomechanical forces to the head or neck that lead to a broad range of neurologic symptoms and impaired cognitive function. Although most individuals recover within weeks, some develop chronic symptoms. The heterogeneity of both the clinical presentation and the underlying brain injury profile make SRC a challenging condition. Adding to this challenge, there is also a lack of objective and reliable biomarkers to support diagnosis, to inform clinical decision making, and to monitor recovery after SRC. In this review, the authors provide an overview of advanced neuroimaging techniques that provide the sensitivity needed to capture subtle changes in brain structure, metabolism, function, and perfusion after SRC. This is followed by a discussion of emerging neuroimaging techniques, as well as current efforts of international research consortia committed to the study of SRC. Finally, the authors emphasize the need for advanced multimodal neuroimaging to develop objective biomarkers that will inform targeted treatment strategies after SRC.
Identifiants
pubmed: 36930218
doi: 10.1097/WNP.0000000000000864
pii: 00004691-202307000-00004
pmc: PMC10329721
mid: NIHMS1690889
doi:
Substances chimiques
Biomarkers
0
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
398-407Subventions
Organisme : NINDS NIH HHS
ID : R01 NS100952
Pays : United States
Informations de copyright
Copyright © 2023 by the American Clinical Neurophysiology Society.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to disclose.
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