Fundus topographical distribution patterns of ocular toxoplasmosis.
Choroid
Imaging
Infection
Inflammation
Retina
Journal
The British journal of ophthalmology
ISSN: 1468-2079
Titre abrégé: Br J Ophthalmol
Pays: England
ID NLM: 0421041
Informations de publication
Date de publication:
20 Mar 2024
20 Mar 2024
Historique:
received:
25
10
2022
accepted:
03
03
2023
pubmed:
18
3
2023
medline:
18
3
2023
entrez:
17
3
2023
Statut:
epublish
Résumé
To establish topographic maps and determine fundus distribution patterns of ocular toxoplasmosis (OT) lesions. In this retrospective study, patients who presented with OT to ophthalmology clinics from four countries (Argentina, Turkey, UK, USA) were included. Size, shape and location of primary (1°)/recurrent (2°) and active/inactive lesions were converted into a two-dimensional retinal chart by a retinal drawing software. A final contour map of the merged image charts was then created using a custom Matlab programme. Descriptive analyses were performed. 984 lesions in 514 eyes of 464 subjects (53% women) were included. Mean area of all 1° and 2° lesions was 5.96±12.26 and 5.21±12.77 mm The 1° lesions were larger than 2° lesions. The 2° lesions were not significantly closer to fovea than 1° lesions. Temporal quadrant and macular region were found to be densely affected underlining the vision threatening nature of the disease.
Sections du résumé
BACKGROUND
BACKGROUND
To establish topographic maps and determine fundus distribution patterns of ocular toxoplasmosis (OT) lesions.
METHODS
METHODS
In this retrospective study, patients who presented with OT to ophthalmology clinics from four countries (Argentina, Turkey, UK, USA) were included. Size, shape and location of primary (1°)/recurrent (2°) and active/inactive lesions were converted into a two-dimensional retinal chart by a retinal drawing software. A final contour map of the merged image charts was then created using a custom Matlab programme. Descriptive analyses were performed.
RESULTS
RESULTS
984 lesions in 514 eyes of 464 subjects (53% women) were included. Mean area of all 1° and 2° lesions was 5.96±12.26 and 5.21±12.77 mm
CONCLUSION
CONCLUSIONS
The 1° lesions were larger than 2° lesions. The 2° lesions were not significantly closer to fovea than 1° lesions. Temporal quadrant and macular region were found to be densely affected underlining the vision threatening nature of the disease.
Identifiants
pubmed: 36931697
pii: bjo-2022-322747
doi: 10.1136/bjo-2022-322747
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
530-535Subventions
Organisme : Medical Research Council
ID : MR/T019050/1
Pays : United Kingdom
Informations de copyright
© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.