Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders.

Female Pregnancy Child, Preschool Humans Brain / diagnostic imaging Mental Disorders / genetics Neuroimaging / methods Phenotype
Childhood Genetics Imaging Infant Magnetic resonance imaging Pediatric

Journal

Biological psychiatry
ISSN: 1873-2402
Titre abrégé: Biol Psychiatry
Pays: United States
ID NLM: 0213264

Informations de publication

Date de publication:
15 05 2023
Historique:
received: 15 07 2022
revised: 09 01 2023
accepted: 11 01 2023
medline: 2 5 2023
pubmed: 18 3 2023
entrez: 17 3 2023
Statut: ppublish

Résumé

Imaging genetics provides an opportunity to discern associations between genetic variants and brain imaging phenotypes. Historically, the field has focused on adults and adolescents; very few imaging genetics studies have focused on brain development in infancy and early childhood (from birth to age 6 years). This is an important knowledge gap because developmental changes in the brain during the prenatal and early postnatal period are regulated by dynamic gene expression patterns that likely play an important role in establishing an individual's risk for later psychiatric illness and neurodevelopmental disabilities. In this review, we summarize findings from imaging genetics studies spanning from early infancy to early childhood, with a focus on studies examining genetic risk for neuropsychiatric disorders. We also introduce the Organization for Imaging Genomics in Infancy (ORIGINs), a working group of the ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) consortium, which was established to facilitate large-scale imaging genetics studies in infancy and early childhood.

Identifiants

DOI: 10.1016/j.biopsych.2023.01.013 PMID: 36932005 PMC: PMC10136952
pubmed: 36932005
pii: S0006-3223(23)00040-9
doi: 10.1016/j.biopsych.2023.01.013
pmc: PMC10136952
pii:
doi:

Types de publication

Meta-Analysis Journal Article Review Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

905-920

Subventions

Organisme : NIH HHS
ID : UH3 OD023349
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH107652
Pays : United States
Organisme : NICHD NIH HHS
ID : R00 HD100593
Pays : United States
Organisme : NIAAA NIH HHS
ID : R01 AA026834
Pays : United States
Organisme : NCRR NIH HHS
ID : UL1 RR025758
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH109662
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD055741
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH105538
Pays : United States
Organisme : NIMH NIH HHS
ID : U01 MH110274
Pays : United States
Organisme : NIH HHS
ID : UG3 OD023349
Pays : United States
Organisme : NICHD NIH HHS
ID : T32 HD040127
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH123716
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH121877
Pays : United States
Organisme : Wellcome Trust
ID : 203525/Z/16/Z
Pays : United Kingdom
Organisme : NICHD NIH HHS
ID : R01 HD060628
Pays : United States
Organisme : NIAAA NIH HHS
ID : R21 AA023887
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL155744
Pays : United States
Organisme : NIH HHS
ID : UG3 OD023313
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD065762
Pays : United States
Organisme : NICHD NIH HHS
ID : P30 HD003110
Pays : United States

Informations de copyright

Copyright © 2023 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

Références

Nat Rev Neurosci. 2008 Jun;9(6):437-52
pubmed: 18478032
Hum Brain Mapp. 2017 Sep;38(9):4444-4458
pubmed: 28580697
PLoS One. 2018 Jan 5;13(1):e0190602
pubmed: 29304146
Int J Mol Sci. 2020 Jan 16;21(2):
pubmed: 31963327
Cereb Cortex. 2021 Mar 5;31(4):1888-1897
pubmed: 33230560
Nat Commun. 2017 Sep 5;8(1):428
pubmed: 28874660
Iran J Psychiatry. 2020 Oct;15(4):286-296
pubmed: 33240378
Am J Psychiatry. 2015 Feb 1;172(2):163-72
pubmed: 25320962
Transl Psychiatry. 2016 Jan 19;6:e716
pubmed: 26784970
PLoS Genet. 2010 May 06;6(5):e1000932
pubmed: 20463879
Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1223-8
pubmed: 20133824
Cereb Cortex. 2009 Nov;19(11):2728-35
pubmed: 19299253
Nature. 2011 Oct 26;478(7370):483-9
pubmed: 22031440
Front Mol Neurosci. 2018 Apr 12;11:119
pubmed: 29706865
Brain Commun. 2020 Jul 08;2(2):fcaa092
pubmed: 32954337
Dev Cogn Neurosci. 2022 Feb;53:101058
pubmed: 34999505
Nat Rev Neurosci. 2018 Feb 16;19(3):123-137
pubmed: 29449712
Hum Genet. 2013 Apr;132(4):461-71
pubmed: 23329067
Transl Psychiatry. 2021 Mar 15;11(1):170
pubmed: 33723212
Neuropsychopharmacology. 2021 Jan;46(2):470-477
pubmed: 32688365
Lancet Neurol. 2007 Jun;6(6):494-500
pubmed: 17509484
J Neurosci. 2007 Sep 19;27(38):10196-209
pubmed: 17881525
Brain Struct Funct. 2021 Apr;226(3):919-925
pubmed: 33474578
Sci Rep. 2019 Feb 13;9(1):1976
pubmed: 30760829
Schizophr Bull. 2009 May;35(3):528-48
pubmed: 19223657
Nat Genet. 2016 Oct;48(10):1284-1287
pubmed: 27571263
Biochim Biophys Acta. 2010 Aug;1801(8):806-18
pubmed: 20170744
Eur J Hum Genet. 2016 Jun;24(6):944-8
pubmed: 26508570
Twin Res Hum Genet. 2012 Jun;15(3):336-50
pubmed: 22856369
Nat Neurosci. 2022 Apr;25(4):421-432
pubmed: 35383335
Brain Commun. 2022 Mar 08;4(2):fcac056
pubmed: 35402911
Biol Psychiatry. 2017 Aug 1;82(3):165-175
pubmed: 28283186
Neuropsychopharmacology. 2018 Feb;43(3):564-570
pubmed: 28975925
EMBO J. 2011 Aug 26;30(19):4071-83
pubmed: 21873981
J Neurosci Res. 2005 Dec 15;82(6):762-70
pubmed: 16273547
Cereb Cortex. 2014 May;24(5):1230-46
pubmed: 23283688
Annu Rev Pathol. 2015;10:111-44
pubmed: 25621659
J Neurochem. 2011 May;117(4):735-46
pubmed: 21395585
Neuropsychol Rev. 2015 Mar;25(1):27-46
pubmed: 25672928
Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E619-E628
pubmed: 28069946
Cereb Cortex. 2023 Apr 4;33(8):4829-4843
pubmed: 36190430
Menopause. 2010 Jul;17(4):874-86
pubmed: 20616674
Mol Psychiatry. 2021 Nov;26(11):6845-6867
pubmed: 33863995
Arch Gen Psychiatry. 2008 Jul;65(7):785-93
pubmed: 18606951
Brain Behav Immun. 2021 Jul;95:154-167
pubmed: 33737172
Am J Hum Genet. 2017 Apr 6;100(4):635-649
pubmed: 28366442
Proc Natl Acad Sci U S A. 2021 Feb 16;118(7):
pubmed: 33558239
Brain Imaging Behav. 2014 Jun;8(2):234-50
pubmed: 24077983
Brain Behav. 2016 Apr 02;6(7):e00434
pubmed: 27110435
Brain Imaging Behav. 2015 Mar;9(1):128-40
pubmed: 25744101
Front Psychiatry. 2022 Mar 21;13:797329
pubmed: 35386517
Proc Natl Acad Sci U S A. 1986 Jun;83(12):4364-8
pubmed: 3459179
Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13744-13749
pubmed: 29229843
iScience. 2021 Jun 11;24(7):102708
pubmed: 34258550
Am J Hum Genet. 2019 Sep 5;105(3):640-657
pubmed: 31402090
Dev Psychopathol. 2015 Feb;27(1):137-50
pubmed: 25640836
Trends Mol Med. 2011 Dec;17(12):699-706
pubmed: 22015021
Brain Imaging Behav. 2020 Feb;14(1):213-225
pubmed: 30393836
Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18026-31
pubmed: 22003128
BioData Min. 2013 Oct 16;6(1):18
pubmed: 24131735
Cereb Cortex. 2021 Jan 5;31(2):933-948
pubmed: 33009551
BMC Genet. 2013 May 09;14:39
pubmed: 23656885
Pediatrics. 2014 Jun;133(6):e1655-63
pubmed: 24819575
Biol Psychiatry. 2022 Aug 15;92(4):299-313
pubmed: 35489875
Cell. 2019 Mar 21;177(1):162-183
pubmed: 30901538
Cereb Cortex. 2022 Jul 21;32(15):3206-3223
pubmed: 34952542
Neuroimage. 2010 Nov 15;53(3):1135-46
pubmed: 20006715
Cereb Cortex. 2020 Nov 3;30(12):6121-6134
pubmed: 32676648
Biochim Biophys Acta. 2012 Apr;1821(4):607-17
pubmed: 22289388
Neuroimage. 2019 Jan 15;185:802-812
pubmed: 29673965
Cereb Cortex. 2017 May 1;27(5):3080-3092
pubmed: 28334351
JAMA Neurol. 2014 Jan;71(1):11-22
pubmed: 24276092
Biochim Biophys Acta. 2011 Feb;1809(2):128-40
pubmed: 20674814
Twin Res Hum Genet. 2013 Oct;16(5):923-30
pubmed: 23919982
Hum Brain Mapp. 2018 Dec;39(12):4998-5013
pubmed: 30144223
Neuroimage. 2015 May 1;111:123-35
pubmed: 25700954
Hum Brain Mapp. 2021 Apr 15;42(6):1583-1593
pubmed: 33528897
Hum Brain Mapp. 2017 Apr;38(4):2026-2036
pubmed: 28032374
BJOG. 2013 Sep;120 Suppl 2:27-32, v
pubmed: 23841904
Signal Transduct Target Ther. 2021 Aug 31;6(1):325
pubmed: 34465723
Genome Res. 2015 Jan;25(1):142-54
pubmed: 25378250
Neuron. 2014 Jan 22;81(2):321-32
pubmed: 24373884
J Neurosci. 2014 Aug 20;34(34):11288-96
pubmed: 25143609
Neuropsychol Rev. 2015 Mar;25(1):63-96
pubmed: 25773500
Neurology. 2016 Aug 9;87(6):585-94
pubmed: 27412137
Trends Genet. 2021 Dec;37(12):1056-1059
pubmed: 34400010
World J Biol Psychiatry. 2022 Oct;23(8):601-612
pubmed: 34895032
Neuroimage. 2008 Jul 15;41(4):1177-83
pubmed: 18486492
Hum Brain Mapp. 2010 Aug;31(8):1174-82
pubmed: 20063301
Biol Psychiatry. 2020 Aug 1;88(3):236-247
pubmed: 32143829
Twin Res Hum Genet. 2010 Aug;13(4):370-80
pubmed: 20707707
Neuroimage. 2020 Nov 15;222:117243
pubmed: 32822813
Nature. 2014 Apr 24;508(7497):469-76
pubmed: 24759409
Philos Trans R Soc Lond B Biol Sci. 2006 Sep 29;361(1473):1545-64
pubmed: 16939974
Transl Psychiatry. 2017 Aug 1;7(8):e1188
pubmed: 28763065
Hum Brain Mapp. 2015 Oct;36(10):3959-72
pubmed: 26147340
Nat Neurosci. 2016 Dec;19(12):1569-1582
pubmed: 27694991
J Psychiatry Neurosci. 2020 Nov 18;46(1):E154-E163
pubmed: 33206040
Brain. 2019 Dec 1;142(12):3806-3833
pubmed: 31665242
PLoS One. 2012;7(4):e32316
pubmed: 22514599
J Neurosci Res. 2020 Dec;98(12):2529-2540
pubmed: 32901998
Mol Chem Neuropathol. 1993 Aug;19(3):235-48
pubmed: 8397584
Transl Psychiatry. 2023 Apr 10;13(1):121
pubmed: 37037832
Nat Rev Genet. 2009 Dec;10(12):872-8
pubmed: 19859063
Psychiatry Res Neuroimaging. 2021 Jan 30;307:111207
pubmed: 33168330
Nat Rev Genet. 2019 Aug;20(8):467-484
pubmed: 31068683
Biochim Biophys Acta. 2014 Feb;1842(2):304-17
pubmed: 24275555
Transl Psychiatry. 2020 Mar 20;10(1):100
pubmed: 32198361
Commun Biol. 2022 Jan 20;5(1):80
pubmed: 35058554
Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17089-94
pubmed: 24082094
Cereb Cortex. 2017 Dec 1;27(12):5626-5634
pubmed: 27913429

Auteurs

Ann M Alex (AM)

Institute for Quantitative Health Sciences and Engineering, Michigan State University, East Lansing, Michigan.

Claudia Buss (C)

Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Medical Psychology, Berlin, Germany; Department of Pediatrics, University of California Irvine, Irvine, California; Development, Health and Disease Research Program, University of California Irvine, Irvine, California.

Elysia Poggi Davis (EP)

Department of Pediatrics, University of California Irvine, Irvine, California; Department of Psychology, University of Denver, Denver, Colorado.

Gustavo de Los Campos (GL)

Institute for Quantitative Health Sciences and Engineering, Michigan State University, East Lansing, Michigan; Departments of Epidemiology & Biostatistics, Michigan State University, East Lansing, Michigan; Department of Statistics & Probability, Michigan State University, East Lansing, Michigan.

Kirsten A Donald (KA)

Division of Developmental Paediatrics, Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa; Neuroscience Institute, University of Cape Town, Cape Town, South Africa.

Damien A Fair (DA)

Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, Minnesota; Institute of Child Development, College of Education and Human Development, University of Minnesota, Minneapolis, Minnesota; Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota.

Nadine Gaab (N)

Harvard Graduate School of Education, Harvard University, Cambridge, Massachusetts.

Wei Gao (W)

Cedars-Sinai Biomedical Imaging Research Institute, Los Angeles, California; Departments of Biomedical Sciences and Imaging, Cedars-Sinai Medical Center, Los Angeles, California.

John H Gilmore (JH)

Department of Psychiatry, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina.

Jessica B Girault (JB)

Department of Psychiatry, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina; Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Carrboro, North Carolina.

Karen Grewen (K)

Department of Psychiatry, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina.

Nynke A Groenewold (NA)

Neuroscience Institute, University of Cape Town, Cape Town, South Africa; South African Medical Research Council Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa; Department of Paediatrics and Child Health, University of Cape Town, Faculty of Health Sciences, Cape Town, South Africa.

Benjamin L Hankin (BL)

Psychology Department, University of Illinois Urbana,-Champaign, Illinois.

Jonathan Ipser (J)

Neuroscience Institute, University of Cape Town, Cape Town, South Africa.

Shreya Kapoor (S)

Research Group Learning in Early Childhood, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.

Pilyoung Kim (P)

Department of Psychology, University of Denver, Denver, Colorado.

Weili Lin (W)

Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Shan Luo (S)

Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California; Department of Psychology, University of Southern California, Los Angeles, California; Center for Endocrinology, Diabetes and Metabolism, Children's Hospital Los Angeles, Los Angeles, California.

Elizabeth S Norton (ES)

Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois; Department of Medical Social Sciences and Institute for Innovations in Developmental Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Thomas G O'Connor (TG)

Departments of Psychiatry, Psychology, Neuroscience, Obstetrics and Gynecology, University of Rochester, Rochester, New York.

Joseph Piven (J)

Department of Psychiatry, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina; Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Carrboro, North Carolina.

Anqi Qiu (A)

Department of Biomedical Engineering, National University of Singapore, Singapore; NUS (Suzhou) Research Institute, National University of Singapore, China; the Institute for Health, National University of Singapore, Singapore; School of Computer Engineering and Science, Shanghai University, Shanghai, China; Institute of Data Science, National University of Singapore, Singapore; Department of Biomedical Engineering, the Johns Hopkins University, Baltimore, Maryland.

Jerod M Rasmussen (JM)

Department of Pediatrics, University of California Irvine, Irvine, California; Development, Health and Disease Research Program, University of California Irvine, Irvine, California.

Michael A Skeide (MA)

Department of Psychiatry, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina; Research Group Learning in Early Childhood, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.

Dan J Stein (DJ)

South African Medical Research Council Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, University of Cape Town, Cape Town, South Africa; Neuroscience Institute, University of Cape Town, Cape Town, South Africa.

Martin A Styner (MA)

Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Paul M Thompson (PM)

Imaging Genetics Center, Stevens Neuroimaging & Informatics Institute, Keck School of Medicine of University of the Sunshine Coast, Marina del Rey, California.

Laurie Wakschlag (L)

Department of Medical Social Sciences and Institute for Innovations in Developmental Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Rebecca Knickmeyer (R)

Institute for Quantitative Health Sciences and Engineering, Michigan State University, East Lansing, Michigan; Department of Pediatrics and Human Development, Michigan State University, East Lansing, Michigan. Electronic address: knickmey@msu.edu.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Genetic Influences on the Developing Young...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Enfant d'âge préscolaire › Genetic Influences on the Developing Young...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Genetic Influences on the Developing Young...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Genetic Influences on the Developing Young...
questionsmedicales.fr › Troubles mentaux › Genetic Influences on the Developing Young...
questionsmedicales.fr › Techniques d'investigation › Neuroimagerie › Genetic Influences on the Developing Young...
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Genetic Influences on the Developing Young...