Neuroimaging Investigations of Obesity: a Review of the Treatment of Sex from 2010.
Affect
Co-occurrence analysis
Motor
Multimodal neuroimaging
Obesity
Sex differences
Journal
Current obesity reports
ISSN: 2162-4968
Titre abrégé: Curr Obes Rep
Pays: United States
ID NLM: 101578283
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
accepted:
15
02
2023
medline:
12
6
2023
pubmed:
19
3
2023
entrez:
18
3
2023
Statut:
ppublish
Résumé
To summarize the results of adult obesity neuroimaging studies (structural, resting-state, task-based, diffusion tensor imaging) published from 2010, with a focus on the treatment of sex as an important biological variable in the analysis, and identify gaps in sex difference research. Neuroimaging studies have shown obesity-related changes in brain structure, function, and connectivity. However, relevant factors such as sex are often not considered. We conducted a systematic review and keyword co-occurrence analysis. Literature searches identified 6281 articles, of which 199 met inclusion criteria. Among these, only 26 (13%) considered sex as an important variable in the analysis, directly comparing the sexes (n = 10; 5%) or providing single-sex/disaggregated data (n = 16, 8%); the remaining studies controlled for sex (n = 120, 60%) or did not consider sex in the analysis (n = 53, 27%). Synthesizing sex-based results, obesity-related parameters (e.g., body mass index, waist circumference, obese status) may be generally associated with more robust morphological alterations in men and more robust structural connectivity alterations in women. Additionally, women with obesity generally expressed increased reactivity in affect-related regions, while men with obesity generally expressed increased reactivity in motor-related regions; this was especially true under a fed state. The keyword co-occurrence analysis indicated that sex difference research was especially lacking in intervention studies. Thus, although sex differences in the brain associated with obesity are known to exist, a large proportion of the literature informing the research and treatment strategies of today has not specifically examined sex effects, which is needed to optimize treatment.
Identifiants
pubmed: 36933153
doi: 10.1007/s13679-023-00498-0
pii: 10.1007/s13679-023-00498-0
pmc: PMC10250271
doi:
Types de publication
Systematic Review
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
163-174Subventions
Organisme : NIMHD NIH HHS
ID : R01 MD015904
Pays : United States
Organisme : NIDDK NIH HHS
ID : R03 DK121025
Pays : United States
Organisme : NIDDK NIH HHS
ID : K23 DK106528
Pays : United States
Informations de copyright
© 2023. The Author(s).
Références
Obesity (Silver Spring). 2016 Oct;24(10):2057-63
pubmed: 27542906
Obesity (Silver Spring). 2019 Nov;27(11):1846-1855
pubmed: 31689011
Hum Brain Mapp. 2016 Nov;37(11):3745-3756
pubmed: 27400738
Lancet. 2016 Aug 20;388(10046):776-86
pubmed: 27423262
Neuroradiol J. 2020 Oct;33(5):400-409
pubmed: 32666872
J Am Coll Cardiol. 2022 Apr 19;79(15):1492-1505
pubmed: 35422246
Front Hum Neurosci. 2015 Jul 01;9:372
pubmed: 26190989
Diabetes Care. 2016 Oct;39(10):1804-10
pubmed: 27489336
Appetite. 2018 Jan 1;120:431-441
pubmed: 28958900
Int Psychogeriatr. 2015 Jan;27(1):121-30
pubmed: 25263181
NCHS Data Brief. 2020 Feb;(360):1-8
pubmed: 32487284
Diabetes. 2016 Oct;65(10):2943-53
pubmed: 27385157
Physiol Behav. 2012 Feb 28;105(4):1028-34
pubmed: 22155218
PLoS One. 2017 Mar 22;12(3):e0172778
pubmed: 28328983
Obesity (Silver Spring). 2018 Feb;26(2):362-367
pubmed: 29239138
Int J Obes (Lond). 2013 Nov;37(11):1435-42
pubmed: 23459322
Obesity (Silver Spring). 2015 Jul;23(7):1422-8
pubmed: 26053145
Int J Obes (Lond). 2015 Oct;39(10):1509-14
pubmed: 26041696
PLoS One. 2014 Oct 03;9(10):e108180
pubmed: 25279729
Int J Obes (Lond). 2016 Oct;40(10):1558-1565
pubmed: 27200505
JAMA. 2001 Sep 12;286(10):1195-200
pubmed: 11559264
Appetite. 2019 Feb 1;133:18-23
pubmed: 30312737
Nutr Diabetes. 2015 Jan 19;5:e148
pubmed: 25599560
Neurology. 2019 Feb 5;92(6):e594-e600
pubmed: 30626649
Physiol Behav. 2018 May 1;188:1-10
pubmed: 29421336
Hum Brain Mapp. 2010 Jul;31(7):1052-64
pubmed: 19998366
Nutrients. 2018 Nov 15;10(11):
pubmed: 30445718
Cell Metab. 2019 Jan 8;29(1):39-49.e4
pubmed: 30344017
Front Hum Neurosci. 2019 Oct 17;13:360
pubmed: 31680912
Neuroscience. 2020 Nov 1;447:94-112
pubmed: 32798591
Psychosom Med. 2012 Sep;74(7):682-90
pubmed: 22879428
Nutrients. 2020 Jan 02;12(1):
pubmed: 31906475
Obes Sci Pract. 2017 Dec 29;4(1):97-105
pubmed: 29479469
Neurology. 2019 Aug 20;93(8):e791-e803
pubmed: 31341005
Biol Psychiatry. 2017 May 1;81(9):789-796
pubmed: 26809248
Nutr Diabetes. 2014 Sep 01;4:e129
pubmed: 25177910
PLoS One. 2013;8(3):e59114
pubmed: 23555620
Food Res Int. 2019 Nov;125:108547
pubmed: 31554096
Obesity (Silver Spring). 2020 Jul;28(7):1263-1269
pubmed: 32427420
Int J Obes (Lond). 2012 May;36(5):627-37
pubmed: 22064161
Psychiatry Res. 2012 Apr 30;202(1):77-9
pubmed: 22595506
Neurotoxicol Teratol. 2015 Nov-Dec;52(Pt B):236-47
pubmed: 26300399
Neuroimage Clin. 2019;21:101640
pubmed: 30553762
J Neurosci. 2010 Oct 27;30(43):14346-55
pubmed: 20980590
Int J Obes (Lond). 2020 May;44(5):980-989
pubmed: 31740723
J Affect Disord. 2018 Jan 1;225:188-194
pubmed: 28837952
Neuroimage. 2015 Nov 15;122:149-57
pubmed: 26256530
Nutr Res. 2020 Jun;78:27-35
pubmed: 32438221
Neuropsychopharmacology. 2019 Dec;44(13):2155-2158
pubmed: 31527863
Obesity (Silver Spring). 2016 Sep;24(9):1842-8
pubmed: 27430417
Int J Obes (Lond). 2020 May;44(5):1097-1107
pubmed: 31796869
Neuroimage. 2012 Feb 1;59(3):2709-21
pubmed: 22332246
Neuroimage. 2019 Nov 1;201:116006
pubmed: 31299367
Nutrients. 2016 Jan 05;8(1):
pubmed: 26742068
Obesity (Silver Spring). 2019 Jul;27(7):1076-1084
pubmed: 31112370
Neuroimage. 2018 May 15;172:239-249
pubmed: 29378320
Behav Brain Res. 2013 Apr 15;243:91-6
pubmed: 23261871
Int J Obes (Lond). 2016 Nov;40(11):1687-1692
pubmed: 27349694
J Diabetes Complications. 2016 Nov - Dec;30(8):1506-1512
pubmed: 27615667
Front Hum Neurosci. 2019 Aug 27;13:290
pubmed: 31507395
Nutr J. 2020 Jul 30;19(1):78
pubmed: 32731865
Int J Obes (Lond). 2017 Aug;41(8):1185-1195
pubmed: 28360430
Neuroimage. 2018 May 15;172:853-863
pubmed: 29107772
Diabetes Care. 2016 May;39(5):764-71
pubmed: 27208378
Surg Obes Relat Dis. 2020 Jan;16(1):1-9
pubmed: 31679986
Nutrients. 2017 Jul 27;9(8):
pubmed: 28749419
Diabetes Care. 2013 Feb;36(2):394-402
pubmed: 23069840
Neuroimage. 2004;23 Suppl 1:S250-63
pubmed: 15501095
Hum Brain Mapp. 2021 Jun 1;42(8):2393-2398
pubmed: 33660923
PLoS One. 2012;7(9):e45403
pubmed: 23028988
Neuroimage. 2014 Oct 15;100:405-13
pubmed: 24862077
Elife. 2021 Nov 02;10:
pubmed: 34726154
Sci Rep. 2017 Aug 30;7(1):9951
pubmed: 28855582
Neurology. 2019 Aug 27;93(9):e864-e878
pubmed: 31363056
Diabetes Metab Res Rev. 2012 Jan;28(1):76-83
pubmed: 21695767
Front Neurosci. 2018 Oct 11;12:741
pubmed: 30364290
Obes Sci Pract. 2019 Aug 30;5(5):416-436
pubmed: 31687167
Diabetes Obes Metab. 2019 Nov;21(11):2459-2464
pubmed: 31282006
Radiology. 2019 Jun;291(3):763-771
pubmed: 31012815
JAMA Netw Open. 2019 Jun 5;2(6):e196126
pubmed: 31225892
Int J Obes (Lond). 2013 Feb;37(2):230-6
pubmed: 22290540
Obes Sci Pract. 2020 Feb 25;6(3):282-292
pubmed: 32523717
Obesity (Silver Spring). 2018 Feb;26(2):340-350
pubmed: 29280306
Alzheimer Dis Assoc Disord. 2015 Oct-Dec;29(4):279-86
pubmed: 25626634
PLoS One. 2011 Apr 11;6(4):e18544
pubmed: 21494606
Obes Surg. 2018 Aug;28(8):2578-2582
pubmed: 29876838
Int J Obes (Lond). 2016 Apr;40(4):633-8
pubmed: 26568151
Neuroimage. 2019 May 1;191:596-609
pubmed: 30798010
Diabetes Care. 2016 Feb;39(2):214-21
pubmed: 26283736
Front Aging Neurosci. 2019 Aug 02;11:202
pubmed: 31427957
J Endocrinol. 2016 Apr;229(1):1-12
pubmed: 26769912
Nat Commun. 2022 May 18;13(1):2845
pubmed: 35585146
Behav Brain Res. 2015 Feb 1;278:342-7
pubmed: 25448431
Obesity (Silver Spring). 2014 Feb;22(2):337-43
pubmed: 24115765
Diabetes Obes Metab. 2019 Aug;21(8):1956-1966
pubmed: 31050167