Viable mpox virus in the environment of a patient room.

Airborne transmission Environmental contamination Formite Modes of transmission Mpox virus (MPXV) Surface contamination

Journal

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
ISSN: 1878-3511
Titre abrégé: Int J Infect Dis
Pays: Canada
ID NLM: 9610933

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 21 12 2022
revised: 07 03 2023
accepted: 07 03 2023
medline: 5 5 2023
pubmed: 19 3 2023
entrez: 18 3 2023
Statut: ppublish

Résumé

We conducted a prospective environmental surveillance study to investigate the air, surface, dust, and water contamination of a room occupied by a patient infected with mpox virus (MPXV) at various stages of the illness. The patient tested positive for MPXV from a throat swab and skin lesions. Environmental sampling was conducted in a negative pressure room with 12 unidirectional high efficiency particulate air filter (HEPA) air changes per hour and daily cleaning of the surfaces. A total of 179 environmental samples were collected on days 7, 8, 13, and 21 of illness. Among the days of sampling, air, surface, and dust contamination showed the highest contamination rates on day 7 and 8 of illness, with a gradual decline to the lowest contamination level by day 21. Viable MPXV was isolated from surfaces and dust samples and no viable virus was isolated from the air and water samples.

Identifiants

pubmed: 36933611
pii: S1201-9712(23)00092-9
doi: 10.1016/j.ijid.2023.03.016
pmc: PMC10019930
pii:
doi:

Substances chimiques

Dust 0
Water 059QF0KO0R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

40-45

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors have no competing interests to declare.

Auteurs

Kalisvar Marimuthu (K)

National Centre for Infectious Diseases, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: kalisvar_marimuthu@ttsh.com.sg.

Judith Chui Ching Wong (JCC)

Environmental Health Institute, National Environment Agency, Singapore.

Poh Lian Lim (PL)

National Centre for Infectious Diseases, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.

Sophie Octavia (S)

Environmental Health Institute, National Environment Agency, Singapore; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, Australia.

Xiaowei Huan (X)

Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.

Yi Kai Ng (YK)

Environmental Health Institute, National Environment Agency, Singapore.

Jun Jing Yang (JJ)

Environmental Health Institute, National Environment Agency, Singapore.

Stephanie Sutjipto (S)

National Centre for Infectious Diseases, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.

Kyaw Zaw Linn (KZ)

National Centre for Infectious Diseases, Singapore.

Yin Xiang Setoh (YX)

Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Environmental Health Institute, National Environment Agency, Singapore; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane City, Australia.

Chong Hui Clara Ong (CHC)

Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.

Jane Griffiths (J)

Environmental Health Institute, National Environment Agency, Singapore.

Sharifah Farhanah (S)

Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.

Thai Shawn Cheok (TS)

Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.

Nur Ashikin Binti Sulaiman (NAB)

National Centre for Infectious Diseases, Singapore.

Sipaco Barbara Congcong (SB)

National Centre for Infectious Diseases, Singapore.

Erica Sena Neves (ES)

Environmental Health Institute, National Environment Agency, Singapore.

Liang Hui Loo (LH)

Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.

Luqman Hakim (L)

Environmental Health Institute, National Environment Agency, Singapore.

Shuzhen Sim (S)

Environmental Health Institute, National Environment Agency, Singapore.

Merrill Lim (M)

Environmental Health Institute, National Environment Agency, Singapore.

Mohammad Nazeem (M)

Environmental Health Institute, National Environment Agency, Singapore.

Shawn Vasoo (S)

National Centre for Infectious Diseases, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.

Kwok Wai Tham (KW)

Department of the Built Environment, National University of Singapore, Singapore.

Oon Tek Ng (OT)

National Centre for Infectious Diseases, Singapore; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.

Lee Ching Ng (LC)

Environmental Health Institute, National Environment Agency, Singapore; School of Biological Sciences, Nanyang Technological University, Singapore.

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Classifications MeSH