Nucleation of fibronectin fibril assembly requires binding between heparin and the 13th type III module of fibronectin.

extracellular matrix fibronectin heparan sulfate heparin heparin-binding domain matrix assembly type III module

Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
05 2023
Historique:
received: 23 11 2022
revised: 28 02 2023
accepted: 06 03 2023
medline: 29 5 2023
pubmed: 19 3 2023
entrez: 18 3 2023
Statut: ppublish

Résumé

Fibronectin (FN), a critical component of the extracellular matrix, is assembled into fibrils through a cell-mediated process. Heparan sulfate (HS) binds to the III

Identifiants

pubmed: 36933809
pii: S0021-9258(23)00264-8
doi: 10.1016/j.jbc.2023.104622
pmc: PMC10124947
pii:
doi:

Substances chimiques

Fibronectins 0
Heparin 9005-49-6

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

104622

Subventions

Organisme : NIH HHS
ID : S10 OD028592
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007388
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA072720
Pays : United States
Organisme : NIAMS NIH HHS
ID : R01 AR073236
Pays : United States

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest The authors declare that they have no conflicts of interest with the contents of this article.

Auteurs

Benjamin M Lovett (BM)

Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA.

Katherine E Hill (KE)

Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA.

Ellie M Randolph (EM)

Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA.

Luqiong Wang (L)

Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA.

Jean E Schwarzbauer (JE)

Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA. Electronic address: jschwarz@princeton.edu.

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Classifications MeSH