A Unified Therapeutic-Prophylactic Tissue-Engineering Scaffold Demonstrated to Prevent Tumor Recurrence and Overcoming Infection toward Bone Remodeling.


Journal

Advanced materials (Deerfield Beach, Fla.)
ISSN: 1521-4095
Titre abrégé: Adv Mater
Pays: Germany
ID NLM: 9885358

Informations de publication

Date de publication:
Jun 2023
Historique:
revised: 08 03 2023
received: 10 01 2023
medline: 23 6 2023
pubmed: 21 3 2023
entrez: 20 3 2023
Statut: ppublish

Résumé

Osteosarcoma occurs in children and adolescents frequently and leads to a high fatality rate. Although surgical resection is the most common methods in clinic, patients always suffer from tumor metastasis and recurrence and it is difficult for them to self-repair large bone defects. Furthermore, the postoperative infection from bacteria triggers an inflammatory response and hinders the bone-repair process. This work demonstrates a gadolinium (Gd)-complex and molybdenum sulfide (MoS

Identifiants

pubmed: 36939167
doi: 10.1002/adma.202300313
doi:

Substances chimiques

Molybdenum 81AH48963U
Hydrogels 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2300313

Subventions

Organisme : National Natural Science Foundation of China
ID : 52003124
Organisme : National Natural Science Foundation of China
ID : 21971117
Organisme : China Postdoctoral Science Foundation
ID : 2020M680862
Organisme : the Youth Project of Tianjin Natural Science Foundation
ID : 21JCQNJC00280
Organisme : National Key R&D Program of China
ID : 2021YFA1202400
Organisme : Fundamental Research Funds for the Central Universities, Nankai University
ID : ZB19500202
Organisme : Fundamental Research Funds for the Central Universities, Nankai University
ID : 63211042
Organisme : State Key Laboratory of Rare Earth Resource Utilization
ID : RERU2019001
Organisme : 111 Project from China
ID : B18030
Organisme : Tianjin Research Innovation Project for Postgraduate Students
ID : 2019YJSB073
Organisme : the Outstanding Youth Project of Tianjin Natural Science Foundation
ID : 20JCJQJC00130
Organisme : the Key Project of Tianjin Natural Science Foundation
ID : 20JCZDJC00650
Organisme : Open Foundation of State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures
ID : 2022GXYSOF07
Organisme : the Haihe Laboratory of Sustainable Chemical Transformations

Informations de copyright

© 2023 Wiley-VCH GmbH.

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Auteurs

Yongkang Huang (Y)

Tianjin Key Lab for Rare Earth Materials and Applications, Center for Rare Earth and Inorganic Functional Materials, Sensing Interdisciplinary Science Center, School of Materials Science and Engineering & National Institute for Advanced Materials, Nankai University, Tianjin, 300350, P. R. China.
College of Chemistry, Nankai University, Tianjin, 300071, P. R. China.

Xinyun Zhai (X)

Tianjin Key Lab for Rare Earth Materials and Applications, Center for Rare Earth and Inorganic Functional Materials, Sensing Interdisciplinary Science Center, School of Materials Science and Engineering & National Institute for Advanced Materials, Nankai University, Tianjin, 300350, P. R. China.

Tengfei Ma (T)

Tianjin Key Lab for Rare Earth Materials and Applications, Center for Rare Earth and Inorganic Functional Materials, Sensing Interdisciplinary Science Center, School of Materials Science and Engineering & National Institute for Advanced Materials, Nankai University, Tianjin, 300350, P. R. China.

Mengzhen Zhang (M)

Tianjin Key Lab for Rare Earth Materials and Applications, Center for Rare Earth and Inorganic Functional Materials, Sensing Interdisciplinary Science Center, School of Materials Science and Engineering & National Institute for Advanced Materials, Nankai University, Tianjin, 300350, P. R. China.
College of Chemistry, Nankai University, Tianjin, 300071, P. R. China.

Houzhi Yang (H)

Graduate School, Tianjin Medical University, Tianjin, 300070, P. R. China.
Department of Spinal Surgery, Tianjin Union Medical Center, Tianjin, 300131, P. R. China.

Shuai Zhang (S)

Tianjin Key Lab for Rare Earth Materials and Applications, Center for Rare Earth and Inorganic Functional Materials, Sensing Interdisciplinary Science Center, School of Materials Science and Engineering & National Institute for Advanced Materials, Nankai University, Tianjin, 300350, P. R. China.

Junbo Wang (J)

Tianjin Key Lab for Rare Earth Materials and Applications, Center for Rare Earth and Inorganic Functional Materials, Sensing Interdisciplinary Science Center, School of Materials Science and Engineering & National Institute for Advanced Materials, Nankai University, Tianjin, 300350, P. R. China.

Wenguang Liu (W)

School of Materials Science and Engineering, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin, 300354, P. R. China.

Xin Jin (X)

School of Medicine, Nankai University, Tianjin, 300071, P. R. China.

William Weijia Lu (WW)

Research Center for Human Tissue and Organs Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.

Xiaoli Zhao (X)

Research Center for Human Tissue and Organs Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.

Weiyu Hou (W)

Department of Spinal Surgery, Tianjin Union Medical Center, Tianjin, 300131, P. R. China.

Tianwei Sun (T)

Department of Spinal Surgery, Tianjin Union Medical Center, Tianjin, 300131, P. R. China.

Jie Shen (J)

Shenzhen Key Laboratory of Spine Surgery, Department of Spine Surgery, Peking University Shenzhen Hospital, Shenzhen, 518036, P. R. China.

Haobo Pan (H)

Research Center for Human Tissue and Organs Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.

Yaping Du (Y)

Tianjin Key Lab for Rare Earth Materials and Applications, Center for Rare Earth and Inorganic Functional Materials, Sensing Interdisciplinary Science Center, School of Materials Science and Engineering & National Institute for Advanced Materials, Nankai University, Tianjin, 300350, P. R. China.

Chun-Hua Yan (CH)

Tianjin Key Lab for Rare Earth Materials and Applications, Center for Rare Earth and Inorganic Functional Materials, Sensing Interdisciplinary Science Center, School of Materials Science and Engineering & National Institute for Advanced Materials, Nankai University, Tianjin, 300350, P. R. China.
Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Rare Earth Materials Chemistry and Applications, PKU-HKU Joint Laboratory in Rare Earth Materials and Bioinorganic Chemistry, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, P. R. China.
College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, P. R. China.

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