Dynamic transcriptomic responses to divergent acute exercise stimuli in young adults.
exercise physiology
extracellular vesicles
gene expression
skeletal muscle
transcriptomics
Journal
Physiological genomics
ISSN: 1531-2267
Titre abrégé: Physiol Genomics
Pays: United States
ID NLM: 9815683
Informations de publication
Date de publication:
01 04 2023
01 04 2023
Historique:
pmc-release:
01
04
2024
medline:
17
4
2023
pubmed:
21
3
2023
entrez:
20
3
2023
Statut:
ppublish
Résumé
Acute exercise elicits dynamic transcriptional changes that, when repeated, form the fundamental basis of health, resilience, and performance adaptations. While moderate-intensity endurance training combined with conventional resistance training (traditional, TRAD) is often prescribed and recommended by public health guidance, high-intensity training combining maximal-effort intervals with intensive, limited-rest resistance training is a time-efficient alternative that may be used tactically (HITT) to confer similar benefits. Mechanisms of action of these distinct stimuli are incompletely characterized and have not been directly compared. We assessed transcriptome-wide responses in skeletal muscle and circulating extracellular vesicles (EVs) to a single exercise bout in young adults randomized to TRAD (
Identifiants
pubmed: 36939205
doi: 10.1152/physiolgenomics.00144.2022
pmc: PMC10110731
doi:
Banques de données
figshare
['10.6084/m9.figshare.21094795']
Types de publication
Randomized Controlled Trial
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
194-212Subventions
Organisme : RRD VA
ID : IK2 RX002781
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA033572
Pays : United States
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