Artificial Intelligence for Automated Implant Identification in Knee Arthroplasty: A Multicenter External Validation Study Exceeding 3.5 Million Plain Radiographs.

artificial intelligence implant identification knee arthroplasty machine learning revision arthroplasty

Journal

The Journal of arthroplasty
ISSN: 1532-8406
Titre abrégé: J Arthroplasty
Pays: United States
ID NLM: 8703515

Informations de publication

Date de publication:
10 2023
Historique:
received: 14 11 2022
revised: 13 03 2023
accepted: 14 03 2023
medline: 25 9 2023
pubmed: 21 3 2023
entrez: 20 3 2023
Statut: ppublish

Résumé

Surgical management of complications following knee arthroplasty demands accurate and timely identification of implant manufacturer and model. Automated image processing using deep machine learning has been previously developed and internally validated; however, external validation is essential prior to scaling clinical implementation for generalizability. We trained, validated, and externally tested a deep learning system to classify knee arthroplasty systems as one of the 9 models from 4 manufacturers derived from 4,724 original, retrospectively collected anteroposterior plain knee radiographs across 3 academic referral centers. From these radiographs, 3,568 were used for training, 412 for validation, and 744 for external testing. Augmentation was applied to the training set (n = 3,568,000) to increase model robustness. Performance was determined by the area under the receiver operating characteristic curve, sensitivity, specificity, and accuracy. Implant identification processing speed was calculated. The training and testing sets were drawn from statistically different populations of implants (P < .001). After 1,000 training epochs by the deep learning system, the system discriminated 9 implant models with a mean area under the receiver operating characteristic curve of 0.989, accuracy of 97.4%, sensitivity of 89.2%, and specificity of 99.0% in the external testing dataset of 744 anteroposterior radiographs. The software classified implants at a mean speed of 0.02 seconds per image. An artificial intelligence-based software for identifying knee arthroplasty implants demonstrated excellent internal and external validation. Although continued surveillance is necessary with implant library expansion, this software represents a responsible and meaningful clinical application of artificial intelligence with immediate potential to globally scale and assist in preoperative planning prior to revision knee arthroplasty.

Sections du résumé

BACKGROUND
Surgical management of complications following knee arthroplasty demands accurate and timely identification of implant manufacturer and model. Automated image processing using deep machine learning has been previously developed and internally validated; however, external validation is essential prior to scaling clinical implementation for generalizability.
METHODS
We trained, validated, and externally tested a deep learning system to classify knee arthroplasty systems as one of the 9 models from 4 manufacturers derived from 4,724 original, retrospectively collected anteroposterior plain knee radiographs across 3 academic referral centers. From these radiographs, 3,568 were used for training, 412 for validation, and 744 for external testing. Augmentation was applied to the training set (n = 3,568,000) to increase model robustness. Performance was determined by the area under the receiver operating characteristic curve, sensitivity, specificity, and accuracy. Implant identification processing speed was calculated. The training and testing sets were drawn from statistically different populations of implants (P < .001).
RESULTS
After 1,000 training epochs by the deep learning system, the system discriminated 9 implant models with a mean area under the receiver operating characteristic curve of 0.989, accuracy of 97.4%, sensitivity of 89.2%, and specificity of 99.0% in the external testing dataset of 744 anteroposterior radiographs. The software classified implants at a mean speed of 0.02 seconds per image.
CONCLUSION
An artificial intelligence-based software for identifying knee arthroplasty implants demonstrated excellent internal and external validation. Although continued surveillance is necessary with implant library expansion, this software represents a responsible and meaningful clinical application of artificial intelligence with immediate potential to globally scale and assist in preoperative planning prior to revision knee arthroplasty.

Identifiants

pubmed: 36940755
pii: S0883-5403(23)00269-3
doi: 10.1016/j.arth.2023.03.039
pii:
doi:

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2004-2008

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Jaret M Karnuta (JM)

University of Pennsylvania, Philadelphia, Pennsylvania.

Hashim J F Shaikh (HJF)

University of Rochester Medical Center, Rochester, New York.

Michael P Murphy (MP)

Loyola Medicine, Chicago, Illinois.

Nicholas M Brown (NM)

Loyola Medicine, Chicago, Illinois.

Andrew D Pearle (AD)

Hospital for Special Surgery, New York, New York.

Danyal H Nawabi (DH)

Hospital for Special Surgery, New York, New York.

Antonia F Chen (AF)

Brigham and Women's Hospital, Boston, Massachusetts.

Prem N Ramkumar (PN)

Hospital for Special Surgery, New York, New York; Long Beach Orthopaedic Institute, Long Beach, California.

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Classifications MeSH