Development of the High-Affinity Carborane-Based Cannabinoid Receptor Type 2 PET Ligand [

Rats Animals Ligands Positron-Emission Tomography / methods Brain / diagnostic imaging Protein Binding Receptors, Cannabinoid / metabolism

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
13 04 2023
Historique:
medline: 14 4 2023
pubmed: 22 3 2023
entrez: 21 3 2023
Statut: ppublish

Résumé

The development of cannabinoid receptor type 2 (CB

Identifiants

DOI: 10.1021/acs.jmedchem.3c00195 PMID: 36944112
pubmed: 36944112
doi: 10.1021/acs.jmedchem.3c00195
doi:

Substances chimiques

Ligands 0
Receptors, Cannabinoid 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

5242-5260

Auteurs

Lea Ueberham (L)

Universität Leipzig, Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry, Johannisallee 29, 04103 Leipzig, Germany.

Daniel Gündel (D)

Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Research Site Leipzig, 04318 Leipzig, Germany.

Martin Kellert (M)

Universität Leipzig, Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry, Johannisallee 29, 04103 Leipzig, Germany.

Winnie Deuther-Conrad (W)

Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Research Site Leipzig, 04318 Leipzig, Germany.

Friedrich-Alexander Ludwig (FA)

Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Research Site Leipzig, 04318 Leipzig, Germany.

Peter Lönnecke (P)

Universität Leipzig, Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry, Johannisallee 29, 04103 Leipzig, Germany.

Aleksandr Kazimir (A)

Universität Leipzig, Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry, Johannisallee 29, 04103 Leipzig, Germany.

Klaus Kopka (K)

Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Research Site Leipzig, 04318 Leipzig, Germany.
Faculty of Chemistry and Food Chemistry, School of Science, TU Dresden, 01069 Dresden, Germany.

Peter Brust (P)

Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Research Site Leipzig, 04318 Leipzig, Germany.
The Lübeck Institute of Experimental Dermatology, University Medical Center Schleswig-Holstein, 23562 Lübeck, Germany.
ORCID: 0000-0001-5555-7058

Rareş-Petru Moldovan (RP)

Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Department of Neuroradiopharmaceuticals, Research Site Leipzig, 04318 Leipzig, Germany.
ORCID: 0000-0003-3119-7945

Evamarie Hey-Hawkins (E)

Universität Leipzig, Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry, Johannisallee 29, 04103 Leipzig, Germany.
ORCID: 0000-0003-4267-0603

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Development of the High-Affinity...
questionsmedicales.fr › Eucaryotes › Animaux › Development of the High-Affinity...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Development of the High-Affinity...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Development of the High-Affinity...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Development of the High-Affinity...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Development of the High-Affinity...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs couplés aux protéines G › Récepteurs de cannabinoïdes › Development of the High-Affinity...