Systemic orchestration of cell size throughout the body: influence of sex and rapamycin exposure in
Drosophila melanogaster
body size
cell size
signalling pathways
target of rapamycin
Journal
Biology letters
ISSN: 1744-957X
Titre abrégé: Biol Lett
Pays: England
ID NLM: 101247722
Informations de publication
Date de publication:
03 2023
03 2023
Historique:
entrez:
22
3
2023
pubmed:
23
3
2023
medline:
24
3
2023
Statut:
ppublish
Résumé
Along with differences in life histories, metazoans have also evolved vast differences in cellularity, involving changes in the molecular pathways controlling the cell cycle. The extent to which the signalling network systemically determines cellular composition throughout the body and whether tissue cellularity is organized locally to match tissue-specific functions are unclear. We cultured genetic lines of
Identifiants
pubmed: 36946132
doi: 10.1098/rsbl.2022.0611
pmc: PMC10031402
doi:
Substances chimiques
TOR Serine-Threonine Kinases
EC 2.7.11.1
Drosophila Proteins
0
Sirolimus
W36ZG6FT64
Insulins
0
Banques de données
figshare
['10.6084/m9.figshare.c.6461041']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
20220611Références
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