Evaluation of SNPs from human IGFBP6 associated with gene expression: an
IGFBP
SNPs
cancer
gene expression
in-silico
mutation
Journal
Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176
Informations de publication
Date de publication:
2023
2023
Historique:
pubmed:
23
3
2023
medline:
23
3
2023
entrez:
22
3
2023
Statut:
ppublish
Résumé
In the bloodstream and in local tissues, most IGF molecules are associated with the one of the members of the IGF-binding protein (IGFBP) family, which are divided into six distinct types. IGF-binding proteins have been demonstrated to either decrease or increase the growth-promoting effects of IGFs on cell culture, by extending their half-life. They alter how IGFs interact with the receptors on their cell surfaces.
Identifiants
pubmed: 36946206
doi: 10.1080/07391102.2023.2192793
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM