Combi-TED: a new trial testing Tedopi


Journal

Future oncology (London, England)
ISSN: 1744-8301
Titre abrégé: Future Oncol
Pays: England
ID NLM: 101256629

Informations de publication

Date de publication:
Dec 2022
Historique:
medline: 28 3 2023
pubmed: 23 3 2023
entrez: 22 3 2023
Statut: ppublish

Résumé

Despite the positive results obtained by first-line chemoimmunotherapy in patients with metastatic non-small-cell lung cancer (NSCLC), only a few second-line options are available after disease progression. Combi-TED is a phase II international study that will assess the efficacy of Tedopi Patients with lung cancer that has spread to other parts of the body are usually treated with a combination of chemotherapy and drugs that stimulate the immune system to kill cancer cells, which is referred to as immunotherapy. If after receiving these drugs the cancer still gets worse, patients have only a few treatment options left and are usually treated with chemotherapy only. Researchers will study if a new medicine called Tedopi

Autres résumés

Type: plain-language-summary (eng)
Patients with lung cancer that has spread to other parts of the body are usually treated with a combination of chemotherapy and drugs that stimulate the immune system to kill cancer cells, which is referred to as immunotherapy. If after receiving these drugs the cancer still gets worse, patients have only a few treatment options left and are usually treated with chemotherapy only. Researchers will study if a new medicine called Tedopi

Identifiants

pubmed: 36946237
doi: 10.2217/fon-2022-0913
doi:

Substances chimiques

Docetaxel 15H5577CQD
Nivolumab 31YO63LBSN

Banques de données

ClinicalTrials.gov
['NCT04884282']

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

4457-4464

Subventions

Organisme : Fondazione Ricerca Traslazionale (FoRT)

Auteurs

Lorenza Landi (L)

Istituto Nazionale Tumori 'Regina Elena' - Via Elio Chianesi n. 53, Roma (RM), 00144, Italy.

Angelo Delmonte (A)

Istituto Romagnolo per lo Studio dei Tumori 'Dino Amadori' (IRST) - Via Piero Maroncelli n. 40, Meldola (FC), 47014, Italy.

Andrea Bonetti (A)

Azienda ULSS 9 Scaligera - Ospedale Mater Salutis Legnago - Via Gianella n.1, Legnago (VR), 37045, Italy.

Giulia Pasello (G)

Department of Surgery, Oncology, & Gastroenterology, University of Padova - Via Giustiniani n. 2 - Padova (PD), 35124, Italy.
Istituto Oncologico Veneto, Via Gattamelata n. 64, Padova (PD), 35128, Italy.

Giulio Metro (G)

Ospedale Santa Maria della Misericordia - Azienda Ospedaliera di Perugia - Via Dottori n. 1, Perugia (PG), 06132, Italy.

Francesca Mazzoni (F)

Azienda Ospedaliero-Universitaria Careggi - Largo G.A. Brambilla n. 3, Firenze (FI), 50134, Italy.

Gloria Borra (G)

Azienda Ospedaliera Universitaria 'Maggiore della Carità' - C.so Mazzini n. 18, Novara (NO), 28100, Italy.

Diana Giannarelli (D)

Biostatistics, Scientific Directorate, Fondazione Policlinico Universitario A. Gemelli, IRCCS - Largo Agostino Gemelli n. 8, Roma (RM) 00168, Italy.

Kalliopi Andrikou (K)

Istituto Romagnolo per lo Studio dei Tumori 'Dino Amadori' (IRST) - Via Piero Maroncelli n. 40, Meldola (FC), 47014, Italy.

Daniela Mangiola (D)

Azienda ULSS 9 Scaligera - Ospedale Mater Salutis Legnago - Via Gianella n.1, Legnago (VR), 37045, Italy.

Stefania Gori (S)

IRCCS Ospedale Sacro Cuore Don Calabria - Via Don A. Sempreboni n. 5, Negrar di Valpolicella (VR), 37024, Italy.

Mario Rosario D'Andrea (MR)

Ospedale San Paolo - Largo Donatori del Sangue n. 1, Civitavecchia (RM), 00053, Italy.

Gabriele Minuti (G)

Istituto Nazionale Tumori 'Regina Elena' - Via Elio Chianesi n. 53, Roma (RM), 00144, Italy.

Blerina Resuli (B)

Istituto Nazionale Tumori 'Regina Elena' - Via Elio Chianesi n. 53, Roma (RM), 00144, Italy.

Anastasia Laudisi (A)

Istituto Nazionale Tumori 'Regina Elena' - Via Elio Chianesi n. 53, Roma (RM), 00144, Italy.

Antonello Vidiri (A)

Istituto Nazionale Tumori 'Regina Elena' - Via Elio Chianesi n. 53, Roma (RM), 00144, Italy.

Laura Conti (L)

Istituto Nazionale Tumori 'Regina Elena' - Via Elio Chianesi n. 53, Roma (RM), 00144, Italy.

Federico Cappuzzo (F)

Istituto Nazionale Tumori 'Regina Elena' - Via Elio Chianesi n. 53, Roma (RM), 00144, Italy.

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