Ultrafast structural changes direct the first molecular events of vision.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
03 2023
Historique:
received: 02 04 2022
accepted: 17 02 2023
medline: 31 3 2023
pubmed: 24 3 2023
entrez: 23 3 2023
Statut: ppublish

Résumé

Vision is initiated by the rhodopsin family of light-sensitive G protein-coupled receptors (GPCRs)

Identifiants

pubmed: 36949205
doi: 10.1038/s41586-023-05863-6
pii: 10.1038/s41586-023-05863-6
pmc: PMC10060157
doi:

Substances chimiques

Heterotrimeric GTP-Binding Proteins EC 3.6.5.1
Retinaldehyde RR725D715M
Rhodopsin 9009-81-8

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

939-944

Subventions

Organisme : NIGMS NIH HHS
ID : P41 GM103393
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2023. The Author(s).

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Auteurs

Thomas Gruhl (T)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Tobias Weinert (T)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Matthew J Rodrigues (MJ)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Christopher J Milne (CJ)

Photon Science Division, Laboratory for Femtochemistry, Paul Scherrer Institute, Villigen PSI, Switzerland.
European XFEL, Schenefeld, Germany.

Giorgia Ortolani (G)

Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.

Karol Nass (K)

Photon Science Division, Laboratory for Femtochemistry, Paul Scherrer Institute, Villigen PSI, Switzerland.

Eriko Nango (E)

Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Japan.
RIKEN SPring-8 Center, Hyogo, Japan.

Saumik Sen (S)

Condensed Matter Theory Group, Laboratory for Theoretical and Computational Physics, Division of Scientific Computing, Theory and Data, Paul Scherrer Institute, Villigen PSI, Switzerland.
Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.

Philip J M Johnson (PJM)

Photon Science Division, Laboratory for Nonlinear Optics, Paul Scherrer Institute, Villigen PSI, Switzerland.

Claudio Cirelli (C)

Photon Science Division, Laboratory for Femtochemistry, Paul Scherrer Institute, Villigen PSI, Switzerland.

Antonia Furrer (A)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.
Biologics Center, Novartis Institutes for Biomedical Research, Basel, Switzerland.

Sandra Mous (S)

Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zurich, Zurich, Switzerland.
Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.

Petr Skopintsev (P)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.
California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA, USA.

Daniel James (D)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.
Department of Physics, Utah Valley University, Orem, UT, USA.

Florian Dworkowski (F)

Photon Science Division, Laboratory for Macromolecules and Bioimaging, Paul Scherrer Institute, Villigen PSI, Switzerland.

Petra Båth (P)

Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.

Demet Kekilli (D)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Dmitry Ozerov (D)

Division Scientific Computing, Theory and Data, Paul Scherrer Institute, Villigen PSI, Switzerland.

Rie Tanaka (R)

RIKEN SPring-8 Center, Hyogo, Japan.
Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Hannah Glover (H)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Camila Bacellar (C)

Photon Science Division, Laboratory for Femtochemistry, Paul Scherrer Institute, Villigen PSI, Switzerland.

Steffen Brünle (S)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.
Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.

Cecilia M Casadei (CM)

Department of Biology, ETH Zurich, Zurich, Switzerland.

Azeglio D Diethelm (AD)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Dardan Gashi (D)

Photon Science Division, Laboratory for Femtochemistry, Paul Scherrer Institute, Villigen PSI, Switzerland.

Guillaume Gotthard (G)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.
Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zurich, Zurich, Switzerland.

Ramon Guixà-González (R)

Condensed Matter Theory Group, Laboratory for Theoretical and Computational Physics, Division of Scientific Computing, Theory and Data, Paul Scherrer Institute, Villigen PSI, Switzerland.
Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.

Yasumasa Joti (Y)

Japan Synchrotron Radiation Research Institute, Hyogo, Japan.

Victoria Kabanova (V)

Photon Science Division, Laboratory for Femtochemistry, Paul Scherrer Institute, Villigen PSI, Switzerland.
Laboratory for Ultrafast X-ray Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Gregor Knopp (G)

Photon Science Division, Laboratory for Femtochemistry, Paul Scherrer Institute, Villigen PSI, Switzerland.

Elena Lesca (E)

Department of Biology, ETH Zurich, Zurich, Switzerland.

Pikyee Ma (P)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Isabelle Martiel (I)

Photon Science Division, Laboratory for Macromolecules and Bioimaging, Paul Scherrer Institute, Villigen PSI, Switzerland.

Jonas Mühle (J)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Shigeki Owada (S)

RIKEN SPring-8 Center, Hyogo, Japan.
Japan Synchrotron Radiation Research Institute, Hyogo, Japan.

Filip Pamula (F)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.
Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.

Daniel Sarabi (D)

Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.

Oliver Tejero (O)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Ching-Ju Tsai (CJ)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Niranjan Varma (N)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Anna Wach (A)

Institute of Nuclear Physics Polish Academy of Sciences, Kraców, Poland.
Operando X-ray Spectroscopy, Energy and Environment Division, Paul Scherrer Institute, Villigen PSI, Switzerland.

Sébastien Boutet (S)

Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.

Kensuke Tono (K)

Japan Synchrotron Radiation Research Institute, Hyogo, Japan.

Przemyslaw Nogly (P)

Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zurich, Zurich, Switzerland.
Dioscuri Center For Structural Dynamics of Receptors, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Kraków, Kraków, Poland.

Xavier Deupi (X)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.
Condensed Matter Theory Group, Laboratory for Theoretical and Computational Physics, Division of Scientific Computing, Theory and Data, Paul Scherrer Institute, Villigen PSI, Switzerland.
Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.

So Iwata (S)

RIKEN SPring-8 Center, Hyogo, Japan.
Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Richard Neutze (R)

Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.

Jörg Standfuss (J)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland.

Gebhard Schertler (G)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland. gebhard.schertler@psi.ch.
Department of Biology, ETH Zurich, Zurich, Switzerland. gebhard.schertler@psi.ch.

Valerie Panneels (V)

Division of Biology and Chemistry, Laboratory for Biomolecular Research, Paul Scherrer Institute, Villigen PSI, Switzerland. valerie.panneels@psi.ch.

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