Design of a generic method for single dual-tracer PET imaging acquisition in clinical routine.
PET
dual-tracer
kinetic modeling
Journal
Physics in medicine and biology
ISSN: 1361-6560
Titre abrégé: Phys Med Biol
Pays: England
ID NLM: 0401220
Informations de publication
Date de publication:
10 04 2023
10 04 2023
Historique:
received:
23
12
2022
accepted:
23
03
2023
medline:
11
4
2023
pubmed:
24
3
2023
entrez:
23
3
2023
Statut:
epublish
Résumé
Using different tracers in positron emission tomography (PET) imaging can bring complementary information on tumor heterogeneities. Ideally, PET images of different tracers should be acquired simultaneously to avoid the bias induced by movement and physiological changes between sequential acquisitions. Previous studies have demonstrated the feasibility of recovering separated PET signals or parameters of two or more tracers injected (quasi-)simultaneously in a single acquisition. In this study, a generic framework in the context of dual-tracer PET acquisition is proposed where no strong kinetic assumptions nor specific tuning of parameters are required. The performances of the framework were assessed through simulations involving the combination of [
Identifiants
pubmed: 36958048
doi: 10.1088/1361-6560/acc723
doi:
Substances chimiques
Fluorodeoxyglucose F18
0Z5B2CJX4D
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Creative Commons Attribution license.