Moderate doses of dietary nitrate elicit greater effects on blood pressure and endothelial function than a high dose: A 13-week pilot study.


Journal

Nutrition, metabolism, and cardiovascular diseases : NMCD
ISSN: 1590-3729
Titre abrégé: Nutr Metab Cardiovasc Dis
Pays: Netherlands
ID NLM: 9111474

Informations de publication

Date de publication:
06 2023
Historique:
received: 16 01 2023
revised: 23 02 2023
accepted: 27 02 2023
medline: 17 5 2023
pubmed: 24 3 2023
entrez: 23 3 2023
Statut: ppublish

Résumé

Few studies have explored the prolonged effects of dietary nitrate on vascular health. This pilot study tested the effects of prolonged consumption (13 weeks) of a range of doses of dietary nitrate (NO Sixty-two overweight or obese older participants (60-75 years) were randomized to the following interventions: (1) high NO This pilot study showed that medium and low doses of NO These findings indicate that supplementation with medium and low, but not high, doses of NO

Sections du résumé

BACKGROUND & AIMS
Few studies have explored the prolonged effects of dietary nitrate on vascular health. This pilot study tested the effects of prolonged consumption (13 weeks) of a range of doses of dietary nitrate (NO
METHODS AND RESULTS
Sixty-two overweight or obese older participants (60-75 years) were randomized to the following interventions: (1) high NO
RESULTS
This pilot study showed that medium and low doses of NO
CONCLUSION
These findings indicate that supplementation with medium and low, but not high, doses of NO

Identifiants

pubmed: 36958967
pii: S0939-4753(23)00084-4
doi: 10.1016/j.numecd.2023.02.024
pii:
doi:

Substances chimiques

Nitrates 0

Types de publication

Randomized Controlled Trial Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1263-1267

Informations de copyright

Copyright © 2023 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Abrar M Babateen (AM)

Human Nutrition & Exercise Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK; Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.

Oliver M Shannon (OM)

Human Nutrition & Exercise Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.

Gerard M O'Brien (GM)

Human Nutrition & Exercise Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.

Dilara Olgacer (D)

Human Nutrition & Exercise Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.

Christina Koehl (C)

Human Nutrition & Exercise Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.

William Fostier (W)

Human Nutrition & Exercise Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.

John C Mathers (JC)

Human Nutrition & Exercise Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.

Mario Siervo (M)

Human Nutrition & Exercise Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK; School of Life Sciences, The University of Nottingham, Nottingham, UK; School of Population Health, Curtin University, Perth, Australia. Electronic address: mario.siervo@curtin.edu.au.

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