Bone, cognitive, and anthropometric profiles and their relation to fracture sites in fallers: a cross-sectional study.

Bone-brain-nervous system interactions DXA Fracture risk assessment Osteoporosis

Journal

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
ISSN: 1433-2965
Titre abrégé: Osteoporos Int
Pays: England
ID NLM: 9100105

Informations de publication

Date de publication:
May 2023
Historique:
received: 05 10 2022
accepted: 08 02 2023
medline: 18 4 2023
pubmed: 25 3 2023
entrez: 24 3 2023
Statut: ppublish

Résumé

Risk factors involved in the different osteoporotic fracture locations are not well-known. The results of this study suggest that there is not one typical profile characterising a particular fracture site but that the occurrence of a fracture may result from the combination of different bone, cognitive, and anthropometrics characteristics. Risk factors involved in the different osteoporotic fracture locations are not well-known. The aim of this study was to identify the differences in bone, cognitive, and anthropometric characteristics between different fracture sites, and to determine whether the site of a fall-related fracture is related to a specific profile. One hundred six women aged 55 years and older with a recent fall-related fracture of the hip (n = 30), humerus (n = 28), wrist (n = 32), or ankle (n = 16) were included. Bone, cognitive, and anthropometric characteristics were first compared among the four fracture site groups. Then, a principal component analysis (PCA) was performed and a comparison was made between the four profiles identified by the first two PCA components. The four fracture site groups differed significantly in their education level, bone mineral density (BMD), body mass index (BMI), fear of falling, and number of errors in the Trail Making Test B, an executive function test. Each of the four fracture sites was found in each four PCA profiles, albeit with a different distribution. The profiles differed mainly by bone, cognitive, and anthropometric characteristics, but also by fear of falling. The fall-related fracture sites differ significantly in anthropometric and bone parameters, in fear of falling and in cognitive abilities. There is not one typical bone, cognitive, and anthropometric profile characterising a particular fall-related site, but rather several possible profiles for a given site. This suggests that the fracture site depends on a combination of several characteristics of the patient.

Identifiants

pubmed: 36959306
doi: 10.1007/s00198-023-06701-1
pii: 10.1007/s00198-023-06701-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

901-913

Subventions

Organisme : Ministère Français de la Santé et de la Prévention
ID : PHRC Programme Hospitalier de Recherche Clinique 2011 no. 2011-A00534-37

Informations de copyright

© 2023. International Osteoporosis Foundation and Bone Health and Osteoporosis Foundation.

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Auteurs

Maëlle Baillet (M)

INSERM, UniCaen, U1075, COMETE, PFRS, Normandie University, Caen, France.
Department of Rheumatology, Caen University Hospital, Caen, France.

Rémy Morello (R)

Department of Statistics and Clinical Research, Caen University Hospital, Caen, France.

Olivier Vittecoq (O)

Department of Rheumatology, Rouen University Hospital, Rouen, France.

Chantal Chavoix (C)

INSERM, UniCaen, U1075, COMETE, PFRS, Normandie University, Caen, France.

Christian Marcelli (C)

INSERM, UniCaen, U1075, COMETE, PFRS, Normandie University, Caen, France. marcelli-c@chu-caen.fr.
Department of Rheumatology, Caen University Hospital, Caen, France. marcelli-c@chu-caen.fr.

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