Retrospective identification of key activities in Uganda's preparedness measures related to the 2018-2020 EVD outbreak in eastern DRC utilizing a framework evaluation tool.


Journal

PLOS global public health
ISSN: 2767-3375
Titre abrégé: PLOS Glob Public Health
Pays: United States
ID NLM: 9918283779606676

Informations de publication

Date de publication:
2022
Historique:
received: 22 11 2021
accepted: 06 04 2022
entrez: 24 3 2023
pubmed: 25 3 2023
medline: 25 3 2023
Statut: epublish

Résumé

Uganda has engaged in numerous capacity building activities related to outbreak preparedness over the last two decades and initiated additional just-in-time preparedness activities after the declaration of the 2018-2020 Ebola Virus Disease (EVD) outbreak in eastern Democratic Republic of Congo (DRC). When Uganda faced importation events related to the DRC outbreak in June-August 2019, the country's ability to prevent sustained in-country transmission was attributed to these long-term investments in preparedness. In order to help prepare countries for similar future scenarios, this analysis reviewed evidence from Uganda's response to the June-August 2019 importation events to identify preparedness activities and capacities that may have enabled Uganda to identify and isolate infected individuals or otherwise prevent further transmission. Content from 143 grey literature documents gathered via targeted and systematic searches from June 6, 2019 to October 29, 2019 and six interviews of key informants were utilized to inform a framework evaluation tool developed for this study. A conceptual framework of Uganda's preparedness activities was developed and evaluated against timelines of Uganda's response activities to the June-August 2019 EVD importation events based on the applicability of a preparedness activity to a response activity and the contribution of the said response activity to the prevention or interruption of transmission. Preparedness activities related to coordination, health facility preparation, case referral and management, laboratory testing and specimen transport, logistics and resource mobilization, and safe and dignified burials yielded consistent success across both importation events while point of entry screening was successful in one importation event but not another according to the framework evaluation tool. Countries facing similar threats should consider investing in these preparedness areas. Future analyses should validate and expand on the use of the framework evaluation tool.

Identifiants

pubmed: 36962240
doi: 10.1371/journal.pgph.0000428
pii: PGPH-D-21-00923
pmc: PMC10021806
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e0000428

Informations de copyright

Copyright: © 2022 Potter et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests.

Références

Health Secur. 2020 Mar/Apr;18(2):105-113
pubmed: 32324074
Int J Environ Res Public Health. 2019 Nov 21;16(23):
pubmed: 31766548
Pan Afr Med J. 2021 Feb 04;38:130
pubmed: 33912300
Global Health. 2020 Mar 19;16(1):24
pubmed: 32192540
MMWR Morb Mortal Wkly Rep. 2020 Jan 10;69(1):10-13
pubmed: 31917781

Auteurs

Christina Potter (C)

Johns Hopkins Center for Health Security, Baltimore, Maryland, United States of America.
Department of Environmental Health & Engineering, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

Lucia Mullen (L)

Johns Hopkins Center for Health Security, Baltimore, Maryland, United States of America.
Department of Environmental Health & Engineering, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

Steven Ssendagire (S)

Makerere University School of Public Health, Kampala, Uganda.

Rhoda K Wanyenze (RK)

Makerere University School of Public Health, Kampala, Uganda.

Alex Riolexus Ario (AR)

Uganda National Institute of Public Health, Kampala, Uganda.
Ministry of Health of Uganda, Kampala, Uganda.

Doreen Tuhebwe (D)

Makerere University School of Public Health, Kampala, Uganda.

Susan Babirye (S)

Makerere University School of Public Health, Kampala, Uganda.

Rebecca Nuwematsiko (R)

Makerere University School of Public Health, Kampala, Uganda.

Jennifer B Nuzzo (JB)

Department of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States of America.

Classifications MeSH