Development and application of a dynamic transmission model of health systems' preparedness and response to COVID-19 in twenty-six Latin American and Caribbean countries.


Journal

PLOS global public health
ISSN: 2767-3375
Titre abrégé: PLOS Glob Public Health
Pays: United States
ID NLM: 9918283779606676

Informations de publication

Date de publication:
2022
Historique:
received: 10 09 2021
accepted: 09 01 2022
entrez: 24 3 2023
pubmed: 25 3 2023
medline: 25 3 2023
Statut: epublish

Résumé

The global impact of COVID-19 has challenged health systems across the world. This situation highlighted the need to develop policies based on scientific evidence to prepare the health systems and mitigate the pandemic. In this scenario, governments were urged to predict the impact of the measures they were implementing, how they related to the population's behavior, and the capacity of health systems to respond to the pandemic. The overarching aim of this research was to develop a customizable and open-source tool to predict the impact of the expansion of COVID-19 on the level of preparedness of the health systems of different Latin American and the Caribbean countries, with two main objectives. Firstly, to estimate the transmission dynamics of COVID-19 and the preparedness and response capacity of health systems in those countries, based on different scenarios and public policies implemented to control, mitigate, or suppress the spread of the epidemic. Secondly, to facilitate policy makers' decisions by allowing the model to adjust its parameters according to the specific pandemic trajectory and policy context. How many infections and deaths are estimated per day?; When are the peaks of cases and deaths expected, according to the different scenarios?; Which occupancy rate will ICU services have along the epidemiological curve?; When is the optimal time increase restrictions in order to prevent saturation of ICU beds?, are some of the key questions that the model can respond, and is publicly accessible through the following link: http://shinyapps.iecs.org.ar/modelo-covid19/. This open-access and open code tool is based on a SEIR model (Susceptible, Exposed, Infected and Recovered). Using a deterministic epidemiological model, it allows to frame potential scenarios for long periods, providing valuable information on the dynamics of transmission and how it could impact on health systems through multiple customized configurations adapted to specific characteristics of each country.

Identifiants

pubmed: 36962316
doi: 10.1371/journal.pgph.0000186
pii: PGPH-D-21-00575
pmc: PMC10021760
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e0000186

Informations de copyright

Copyright: © 2022 Santoro et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

As authors, we have no conflict of interest. We have already stated that the development of the model was founded by IDB but they have not intervened in the design, analysis or results obtained.

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Auteurs

Adrián Santoro (A)

Center for Implementation and Innovation in Health Policies, Institute for Clinical Effectiveness and Health Policy, Autonomous City of Buenos Aires, Argentina.

Alejandro López Osornio (A)

Center for Implementation and Innovation in Health Policies, Institute for Clinical Effectiveness and Health Policy, Autonomous City of Buenos Aires, Argentina.

Ivan Williams (I)

Faculty of Economics, University of Buenos Aires, Autonomous City of Buenos Aires, Argentina.

Martín Wachs (M)

Center for Implementation and Innovation in Health Policies, Institute for Clinical Effectiveness and Health Policy, Autonomous City of Buenos Aires, Argentina.

Cintia Cejas (C)

Center for Implementation and Innovation in Health Policies, Institute for Clinical Effectiveness and Health Policy, Autonomous City of Buenos Aires, Argentina.

Maisa Havela (M)

Center for Implementation and Innovation in Health Policies, Institute for Clinical Effectiveness and Health Policy, Autonomous City of Buenos Aires, Argentina.

Ariel Bardach (A)

Department of Health Technology Assesments (HTA) and Health Economics, Institute for Clinical Effectivenessand Health Policy, Autonomous City of Buenos Aires, Argentina.

Analía López (A)

Center for Implementation and Innovation in Health Policies, Institute for Clinical Effectiveness and Health Policy, Autonomous City of Buenos Aires, Argentina.

Federico Augustovski (F)

Department of Health Technology Assesments (HTA) and Health Economics, Institute for Clinical Effectivenessand Health Policy, Autonomous City of Buenos Aires, Argentina.

Andrés Pichón Riviere (A)

Department of Health Technology Assesments (HTA) and Health Economics, Institute for Clinical Effectivenessand Health Policy, Autonomous City of Buenos Aires, Argentina.

Adolfo Rubinstein (A)

Center for Implementation and Innovation in Health Policies, Institute for Clinical Effectiveness and Health Policy, Autonomous City of Buenos Aires, Argentina.

Classifications MeSH