Optimizing availability of obstetric surgical care in India: A cost-effectiveness analysis examining rates and access to Cesarean sections.
Journal
PLOS global public health
ISSN: 2767-3375
Titre abrégé: PLOS Glob Public Health
Pays: United States
ID NLM: 9918283779606676
Informations de publication
Date de publication:
2022
2022
Historique:
received:
26
09
2021
accepted:
14
11
2022
entrez:
24
3
2023
pubmed:
25
3
2023
medline:
25
3
2023
Statut:
epublish
Résumé
The objective of this study is to assess the cost-effectiveness of three different strategies with different availabilities of cesarean sections (CS). The setting was rural and urban areas of India with varying rates of CS and access to comprehensive emergency obstetric care (CEmOC) for women of reproductive age in India. Three strategies with different access to CEmOC and CS rates were evaluated: (A) India's national average (50.2% access, 17.2% CS rate), (B) rural areas (47.2% access, 12.8% CS rate) and(C) urban areas (55.7% access, 28.2% CS rate). We performed a first-order Monte Carlo simulation using a 1-year cycle time and 34-year time horizon. All inputs were derived from literature. A societal perspective was utilized with a willingness-to-pay threshold of $1,940. The outcome measures were costs and quality-adjusted life years were used to calculate the incremental cost-effectiveness ratio (ICER). Maternal and neonatal outcomes were calculated. Strategy C with the highest access to CEmOC despite the highest CS rate was cost-effective, with an ICER of 354.90. Two-way sensitivity analysis demonstrated this was driven by increased access to CEmOC. The highest CS rate strategy had the highest number of previa, accreta and ICU admissions. The strategy with the lowest access to CEmOC had the highest number of fistulae, uterine rupture, and stillbirths. In conclusion, morbidity and mortality result from lack of access to CEmOC and overuse of CS. While interventions are needed to address both, increasing access to surgical obstetric care drives cost-effectiveness and is paramount to optimize outcomes.
Identifiants
pubmed: 36962905
doi: 10.1371/journal.pgph.0001369
pii: PGPH-D-21-00715
pmc: PMC10021835
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e0001369Informations de copyright
Copyright: © 2022 Roa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Déclaration de conflit d'intérêts
I have read the journal’s policy and the authors of this manuscript have the following competing interests: MGS serves on the board for Pharos Global Health Advisors, has received speaking fees from Meditech and the American Hospital Association. AAB serves on the scientific advisory board for RHIA ventures and has provided consulting services to DARE Bioscience.
Références
Lancet. 2018 Oct 13;392(10155):1341-1348
pubmed: 30322584
Crit Care Med. 1999 Sep;27(9):1754-9
pubmed: 10507594
BMC Med. 2010 Nov 10;8:71
pubmed: 21067593
Lancet. 2016 Oct 8;388(10053):1545-1602
pubmed: 27733282
Lancet. 2006 Oct 28;368(9546):1472-3
pubmed: 17071266
Int J Technol Assess Health Care. 2016 Jan;32(4):241-245
pubmed: 27608529
Lancet. 2010 Feb 6;375(9713):490-9
pubmed: 20071021
JAMA. 2015 Dec 1;314(21):2263-70
pubmed: 26624825
J Health Popul Nutr. 2005 Sep;23(3):266-74
pubmed: 16262024
BMJ Glob Health. 2016 Apr 13;1(1):e000019
pubmed: 28588914
Am J Obstet Gynecol. 2014 Jul;211(1):56.e1-56.e12
pubmed: 24487008
J Indian Med Assoc. 2001 Nov;99(11):634-7
pubmed: 12022205
Reprod Health. 2018 Jan 5;15(1):3
pubmed: 29304867
J Obstet Gynaecol India. 2017 Feb;67(1):42-47
pubmed: 28242967
PLoS One. 2014 Jan 15;9(1):e83331
pubmed: 24454701
BMC Pregnancy Childbirth. 2014 Jul 22;14:243
pubmed: 25052536
Obstet Gynecol. 2012 Aug;120(2 Pt 1):318-24
pubmed: 22825091
J Obstet Gynaecol India. 2016 Oct;66(Suppl 1):295-300
pubmed: 27651620
PLoS Med. 2010 Apr 20;7(4):e1000264
pubmed: 20421922
J Prev Med Hyg. 2011 Dec;52(4):161-73
pubmed: 22442920
J Pregnancy. 2017;2017:5936309
pubmed: 28321338
JRSM Open. 2016 Nov 01;7(11):2054270416663569
pubmed: 27895930
BMJ. 2018 Jan 24;360:k55
pubmed: 29367432
Health Policy Plan. 1998 Sep;13(3):249-62
pubmed: 10187595
Acta Obstet Gynecol Scand. 2017 Apr;96(4):410-420
pubmed: 28107771
BMJ Open. 2013 Jun 20;3(6):
pubmed: 23794591
Oman Med J. 2015 May;30(3):181-6
pubmed: 26171124
J Obstet Gynaecol India. 2012 Feb;62(1):57-61
pubmed: 23372292
PLoS One. 2012;7(4):e34595
pubmed: 22558089
Paediatr Perinat Epidemiol. 2007 Mar;21(2):98-113
pubmed: 17302638
J Health Popul Nutr. 2009 Jun;27(3):368-78
pubmed: 19507752
Acta Obstet Gynecol Scand. 2013 Apr;92(4):461-4
pubmed: 23517217
Obstet Gynecol. 1985 Jul;66(1):89-92
pubmed: 4011075
Obstet Gynecol. 2006 Jun;107(6):1226-32
pubmed: 16738145
J Obstet Gynaecol India. 2019 Apr;69(2):110-114
pubmed: 30956463
Trop Doct. 2015 Jul;45(3):183-7
pubmed: 25979844
Reprod Health. 2015 Jun 21;12:57
pubmed: 26093498
Birth. 2011 Jun;38(2):99-104
pubmed: 21599731
J Health Popul Nutr. 2009 Apr;27(2):249-58
pubmed: 19489419
J Obstet Gynaecol. 2012 Apr;32(3):260-3
pubmed: 22369400
J Matern Fetal Neonatal Med. 2011 Nov;24(11):1341-6
pubmed: 21381881
BMJ. 2005 Nov 12;331(7525):1107
pubmed: 16282407
Soc Sci Med. 1993 Nov;37(10):1223-31
pubmed: 8272901