Patient Confidence and Information Preferences During the Treatment Decision-making Process: Results From a Large Multiple Myeloma Patient Survey Across 12 Countries in Europe and Israel.


Journal

Clinical lymphoma, myeloma & leukemia
ISSN: 2152-2669
Titre abrégé: Clin Lymphoma Myeloma Leuk
Pays: United States
ID NLM: 101525386

Informations de publication

Date de publication:
05 2023
Historique:
received: 30 09 2022
revised: 31 01 2023
accepted: 23 02 2023
medline: 21 4 2023
pubmed: 27 3 2023
entrez: 26 3 2023
Statut: ppublish

Résumé

The relapsing nature of multiple myeloma (MM) means that patients typically receive different and multiple lines of therapy, requiring many treatment decisions over the disease course. The aim of this study was to explore patient confidence and information preferences during the treatment decision-making process. A multinational, cross-sectional survey enrolled patients with MM. It was co-developed and distributed by Myeloma Patients Europe across 12 countries in Europe and Israel from May 2019 to March 2020. Eligibility criteria included a self-reported diagnosis of MM and being able to recall the decision-making process at the start of their latest treatment line. A total of 1559 patients were included, with complete responses received from 1081 (69%) patients. The median age range was 54 to 64 years; there was an equal gender split and 57% had their latest treatment decision made within the past year. Overall, 54% of patients felt "very confident" in the latest treatment decision. Patients deemed the most important information to be safety/tolerability and treatment effectiveness, but the latter was among the least frequently received. Most patients reported that their primary physician treating MM was their main source for all types of information (range, 62%-94%), with 87% of patients reporting a "very good" or "good" relationship with them. Over half of patients felt very confident in their latest treatment decision; however, patients reported not routinely receiving important treatment effectiveness information. Addressing the discrepancies between information that patients receive and consider important may enhance confidence in decision-making.

Sections du résumé

BACKGROUND
The relapsing nature of multiple myeloma (MM) means that patients typically receive different and multiple lines of therapy, requiring many treatment decisions over the disease course. The aim of this study was to explore patient confidence and information preferences during the treatment decision-making process.
PATIENTS AND METHODS
A multinational, cross-sectional survey enrolled patients with MM. It was co-developed and distributed by Myeloma Patients Europe across 12 countries in Europe and Israel from May 2019 to March 2020. Eligibility criteria included a self-reported diagnosis of MM and being able to recall the decision-making process at the start of their latest treatment line.
RESULTS
A total of 1559 patients were included, with complete responses received from 1081 (69%) patients. The median age range was 54 to 64 years; there was an equal gender split and 57% had their latest treatment decision made within the past year. Overall, 54% of patients felt "very confident" in the latest treatment decision. Patients deemed the most important information to be safety/tolerability and treatment effectiveness, but the latter was among the least frequently received. Most patients reported that their primary physician treating MM was their main source for all types of information (range, 62%-94%), with 87% of patients reporting a "very good" or "good" relationship with them.
CONCLUSION
Over half of patients felt very confident in their latest treatment decision; however, patients reported not routinely receiving important treatment effectiveness information. Addressing the discrepancies between information that patients receive and consider important may enhance confidence in decision-making.

Identifiants

pubmed: 36967243
pii: S2152-2650(23)00074-5
doi: 10.1016/j.clml.2023.02.010
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e240-e251.e12

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Ulf-Henrik Mellqvist (UH)

Department of Hematology, Borås Hospital, Borås, Sweden. Electronic address: ulf-henrik.mellqvist@vgregion.se.

H Tilman Steinmetz (HT)

Oncology Cologne, Centre for Hematology and Oncology, Cologne, Germany.

Aurore Perrot (A)

Service d'Hématologie, CHU de Toulouse, IUCT-Oncopole, Toulouse,France.

Erik Aerts (E)

Department of Internal Medicine, Hematology, University Hospital Zurich, Zurich, Switzerland.

Paul Williams (P)

IQVIA, Paris, France.

Ana Vallejo (A)

Myeloma Patients Europe, Brussels, Belgium.

Kate Morgan (K)

Myeloma Patients Europe, Brussels, Belgium.

Ananda Plate (A)

Myeloma Patients Europe, Brussels, Belgium.

Renaud Desgraz (R)

Amgen GmbH, Rotkreuz, Switzerland.

Eva Hellqvist Franck (EH)

Amgen AB, Solna, Sweden.

Lucy De Costa (L)

Global Biostatistical Science, Amgen Ltd., Uxbridge, UK.

Alessandra Brescianini (A)

Amgen GmbH, Rotkreuz, Switzerland.

Heinz Ludwig (H)

Wilhelminen Cancer Research Institute, Wilhelminenspital, Vienna, Austria.

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Classifications MeSH