Erectile dysfunction and exosome therapy.

cavernous nerve injury diabetes erectile dysfunction exosome extracellular vesicle

Journal

Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782

Informations de publication

Date de publication:
2023
Historique:
received: 14 12 2022
accepted: 27 02 2023
medline: 28 3 2023
entrez: 27 3 2023
pubmed: 28 3 2023
Statut: epublish

Résumé

Erectile dysfunction (ED), as a common male disease, can seriously reduce the life quality of men and their partners. With the improvement of human living standards, ED is considered to be an important health issue that plagues men. However, it is difficult for existing therapeutic approaches to meet the needs of all patients, so it is necessary to develop novel treatment strategies. Exosomes, as a class of vesicles secreted by cells with bilayer membrane structure, are involved in various physiological and pathological processes in human body and considered to have great therapeutic potentials. This review summarizes the recent advances on exosome therapy with animal models of ED, and proposes the prospect of future research in order to provide a basis for clinical trials and clinical translation.

Identifiants

pubmed: 36967787
doi: 10.3389/fendo.2023.1123383
pmc: PMC10034068
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1123383

Informations de copyright

Copyright © 2023 Feng, Peng, Deng, Liu and Wang.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Huan Feng (H)

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Shenzhen Huazhong University of Science and Technology Research Institute, Shenzhen, Guangdong, China.

Wei Peng (W)

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Shenzhen Huazhong University of Science and Technology Research Institute, Shenzhen, Guangdong, China.

Zhiyao Deng (Z)

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Shenzhen Huazhong University of Science and Technology Research Institute, Shenzhen, Guangdong, China.

Jihong Liu (J)

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Tao Wang (T)

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Shenzhen Huazhong University of Science and Technology Research Institute, Shenzhen, Guangdong, China.

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Classifications MeSH