Characterization and susceptibility of non-albicans
fungal infection
infection
microbiology
non-albicans Candida
pathogens
Journal
Frontiers in public health
ISSN: 2296-2565
Titre abrégé: Front Public Health
Pays: Switzerland
ID NLM: 101616579
Informations de publication
Date de publication:
2023
2023
Historique:
received:
03
12
2022
accepted:
21
02
2023
medline:
28
3
2023
entrez:
27
3
2023
pubmed:
28
3
2023
Statut:
epublish
Résumé
Invasive fungal infections have presented a challenge in treatment. In the past, it was known that the frontrunner in such infections is This is a two-year observational multi-central descriptive study. Between September 2016 and May of 2018, a total of 1000 isolates were collected from 10 different hospitals distributed all over the country. For the culture, Sabouraud Dextrose Agar was used. Antifungal Susceptibility was evaluated by determining the Minimum Inhibitory Concentration (MIC) in broth (microdilution) of the different antifungal treatments. Out of the 1000 collected isolates, The change of etiology of fungal infections involving a significant increase in NAC cases is alarming due to the different antifungal susceptibility patterns and the lack of local guidelines to guide the treatment. In this context, proper identification of such organisms is of utmost importance. The data presented here can help in establishing guidelines for the treatment of candida infections to decrease morbidity and mortality. Future surveillance data are needed.
Sections du résumé
Background
Invasive fungal infections have presented a challenge in treatment. In the past, it was known that the frontrunner in such infections is
Methods
This is a two-year observational multi-central descriptive study. Between September 2016 and May of 2018, a total of 1000 isolates were collected from 10 different hospitals distributed all over the country. For the culture, Sabouraud Dextrose Agar was used. Antifungal Susceptibility was evaluated by determining the Minimum Inhibitory Concentration (MIC) in broth (microdilution) of the different antifungal treatments.
Results
Out of the 1000 collected isolates,
Conclusion
The change of etiology of fungal infections involving a significant increase in NAC cases is alarming due to the different antifungal susceptibility patterns and the lack of local guidelines to guide the treatment. In this context, proper identification of such organisms is of utmost importance. The data presented here can help in establishing guidelines for the treatment of candida infections to decrease morbidity and mortality. Future surveillance data are needed.
Identifiants
pubmed: 36969669
doi: 10.3389/fpubh.2023.1115055
pmc: PMC10036786
doi:
Substances chimiques
Antifungal Agents
0
Types de publication
Observational Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1115055Informations de copyright
Copyright © 2023 Husni, Bou Zerdan, Samaha, Helou, Mahfouz, Saniour, Hourani, Kolanjian, Afif, Azar, El Jisr, Mokhbat, Abboud, Feghali, Abboud, Matta, Karayakouboglo, Matar, Moghnieh and Daoud.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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