Identification of new oxospiro chromane quinoline-carboxylate antimalarials that arrest parasite growth at ring stage.

Docking & MD simulation Pf3D7 and PfINDO Plasmodium N-myristoyltransferase inhibitors X-ray crystallography homology modeling

Journal

Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176

Informations de publication

Date de publication:
27 Mar 2023
Historique:
entrez: 27 3 2023
pubmed: 28 3 2023
medline: 28 3 2023
Statut: aheadofprint

Résumé

Malaria still threatens half the globe population despite successful Artemisinin-based combination therapy. One of the reasons for our inability to eradicate malaria is the emergence of resistance to current antimalarials. Thus, there is a need to develop new antimalarials targeting

Identifiants

DOI: 10.1080/07391102.2023.2188959 PMID: 36970842
pubmed: 36970842
doi: 10.1080/07391102.2023.2188959
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-22

Auteurs

Ehtesham Jameel (E)

Department of Chemistry, Drug Design and Synthesis Laboratory, Jamia Millia Islamia, New Delhi, India.
ORCID: 0000-0002-6111-2028

Hari Madhav (H)

Department of Chemistry, Drug Design and Synthesis Laboratory, Jamia Millia Islamia, New Delhi, India.
ORCID: 0000-0003-4992-096X

Prakhar Agrawal (P)

International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.

Md Kausar Raza (MK)

Department of Chemistry and Chemical Engineering, California Institute of Technology (Caltech), Pasadena, CA, USA.

Saiema Ahmedi (S)

Medical Mycology Lab, Department of Biosciences, Jamia Millia Islamia, New Delhi, India.

Abdur Rahman (A)

Department of Chemistry, Drug Design and Synthesis Laboratory, Jamia Millia Islamia, New Delhi, India.

Nida Shahid (N)

Department of Chemistry, Jamia Millia Islamia, New Delhi, India.

Kashfa Shaheen (K)

Department of Chemistry, Drug Design and Synthesis Laboratory, Jamia Millia Islamia, New Delhi, India.

Chhaya Haresh Gajra (CH)

International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.

Ashma Khan (A)

Department of Chemistry, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

Md Zubbair Malik (MZ)

School of Computational Biology, Jawaharlal Nehru University, New Delhi, India.

Md Ali Imam (MA)

Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India.

Md Kalamuddin (M)

Medical Mycology Lab, Department of Biosciences, Jamia Millia Islamia, New Delhi, India.

Jitendra Kumar (J)

Department of Chemistry, Sardar Vallabhbhai Patel College, Bhabua, India.
V. K. S. U., Ara, Bihar, India.

Dinesh Gupta (D)

International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.
ORCID: 0000-0002-7548-8835

Shahid M Nayeem (SM)

Department of Chemistry, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

Nikhat Manzoor (N)

Department of Chemistry and Chemical Engineering, California Institute of Technology (Caltech), Pasadena, CA, USA.

Asif Mohammad (A)

International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.

Pawan Malhotra (P)

International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.
ORCID: 0000-0002-7384-6280

Nasimul Hoda (N)

Department of Chemistry, Drug Design and Synthesis Laboratory, Jamia Millia Islamia, New Delhi, India.
ORCID: 0000-0001-9779-2056

Classifications MeSH